Ferulic acid is a botanical antioxidant which helps ameliorate the reliability and degree of protection sunscreens offer in preventing premature aging and cancerous changes.
Ferulic acid is a prime botanical antioxidant indicated for individuals of all skin types and conditions over the age of 25.
Ultraviolet radiation (UVR) present in daylight is responsible for the majority of damage to the skin (about 90%) that results in premature (unnecessary and preventable) aging and skin cancer.
The use of botanical antioxidants in dermatology is growing in popularity because they protect the skin in ways sunscreens and UV-protective clothing cannot.
It is now recognized that even the best sunscreens are only able to prevent around 50% of premature skin aging (fine and deep lines, losses in firmness, contour and the development of hyperpigmentation, among other symptoms and conditions), even if used generously and reapplied throughout the day.
Antioxidants such as ferulic acid protect the entire skin structure, in particular the dermis, where capillaries, collagen and elastin are located, well beyond the reach of superficial sunscreens.
Ferulic acid at a concentration of 0.5% and pH 3.2, as used in Skinceuticals AOX+ Serums, is a botanical agent with a proven ability to prevent permanent skin damage by routine daily exposure to daylight.
Ferulic acid is a hydroxycinnamic acid largely present in plants and also in vegetable foods, such as olives, olive oil, blueberries and blackberries.
Lyophilized extract of the plant Capparis spinosa obtained by methanolic extraction from its flowering buds contains abundant amounts of ferulic acid.
Ferulic acid has been shown to protect phospholipidic biomembranes from UV light-induced peroxidation and to afford significant protection to the skin against UVB-induced erythema in human volunteers.
Topical application of whole Capparis spinosa extract has been shown to reduce UVB-induced skin erythema in healthy humans.
Skincare products containing ferulic acid are used daily, each morning before Sunscreen.
Topical Vitamin C (as Ascorbic Acid, 10% and higher, pH 3.2) also protects against UV Damage.
Skinceuticals AOX+ Serums combine ascorbic with ferulic acid at the right strength in absorbable formulas for greater effects than either ingredient alone (C E Ferulic is especially notable, proven to provide 8 times the skin's normal protection, even without sunscreen use, readily outperforming even Idebenone).
Along with ascorbic acid, ferulic acid is now an integral part of broken capillary treatment protocols, hyperpigmentation treatment, provision of maximum possible protection against premature aging (particularly in individuals with prohibitive allergies to chemical sunscreens) and restoring/developing skin firmness, colour and tone to optimal levels.
Selection of Ferulic Acid References:
Available to patients on request.
Huang MT, Smart RC, Wong CQ, et al. Inhibitory effect of curcumin, chlorogenic acid, caffeic acid, and ferulic acid on tumor promotion in mouse skin by 12-0-tetradecanoylphorbol13-acetate. Cancer Res 1988; 48: 5941-5946.
Saija A, Tomaino A, Trombetta D, et al. In vitro and in vivo evaluation of caffeic and ferulic acids as topical photoprotective agents. Int J Pharm 2000; 199: 39-47.
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