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Perennial / Wisdoms

Skin Care Failures
Theories of Aging
Photoprotection and Sunscreens
Nutritional Co-Factors

Skin Care

Cellex-C
Cetaphil
Darphin [Ref] [New]
Decleor
Dermalogica
Dibi
Gernetic [Notes] [New]
Glyderm
Glytone
IS Clinical
Jan Marini [Notes] [Ref] [New]
Kinerase
Kosmea
La Roche Posay
MD Rx
Obagi
Olos
Phytomer
Skinceuticals [Notes] [Ref] [New]
SkinMedica

Product Types

Facial Cleansers
Antioxidants
Moisturizers
Sunscreens

Facial Skin Condition Treatments

Adult Acne
Open Pores
Broken Capillaries
Dark Circles
Eyelid Toning
Hyperpigmentation
Puffy Eyes
Rosacea

Body Skin Condition Treatments

Breast Firming
Cellulite
Ingrown Hairs
Keratosis Pilaris
Scalp Acne
Stretch Marks

Skin Care Ingredients

Betaglucans
Centella Asiatica
Ferulic Acid
Glutathione
Mexoryl
Nymphae Alba
Peroxidase
Silymarin
Superoxide Dismutase
Telomerase
Browse more ingredients.

Clinical Procedures and Topics

Four Fundamentals
Antioxidants
Botox
Enzyme Exfoliation
Free Radical Damage
Glycolic Acid
Idebenone
Klein Becker
Oxidative Stress
Perricone
Restylane
Smoking
Sun Protection
Topical Vitamin C/Firming
Choices and Needs
Strivectin
Additional clinical skincare topics.

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The skin's matrix may sometimes be referred to as glycosaminoglycans.

The matrix is essential for the support of the collagen and elastin fibers which give skin its bounce and resiliency.

The production and maintenance of glycosaminoglycans, and the inter-cellular matrix, is dependent on dermal hydration.

Moisturizers are usually only epidermal hydrators, and do not exert any therapeutic effect by themselves.

Exceptions include the Hydrators by Jan Marini, which utilize moisturizing ingredients as a base (or delivery vehicle) for scientifically studied active ingredients (importantly these are integrated at the same concentrations as studies).

Most skin does not carry its ideal moisture level, however dry and dehydrated skin, and in particular the dry skin of smokers, are particularly affected.

For this reason, with all other factors being equal, drier skin types will age more rapidly than other skin types and skin aging is mediated by dermal hydration levels.

The quickest and most effective means of raising dermal hydration levels is with Gernetic Hydra-Ger Mask, Gernetic Cells-Life Serum and daily use of Gernetic Synchro.

Effects on the Skin of Glycosaminoglycan Depletion

The loss of glycosaminoglycans from the skin weakens the supportive inter-cellular matrix and results in loose, flaccid and generally unfirm skin, both on the face and body.

Essential fatty acids, implemented internally and topically in skin texture treatment, as well as anti-aging skin treatment using low-glycemic index foods, will increase dermal hydration.

In all cases a combination of internal and topical skin care is required for noticeable results.

Combination supplementation of essential fatty acids and anti-aging skin treatment will produce thicker, smoother skin with more resilience and turgidity than would otherwise be the case.