Elastase: The Unrestrained Thief of Skin Elasticity: Melbourne Dermatology Skin Care

Clinical Procedures and Topics

absent activity aging although analysis anti appearance array available avoid avoidable benefit biology both break breakdown cannot chemical class collagen communicates compared components compound concentrations consider considerable constituent contraction decrease degree depending dermal deteriorate determines down effect elastase elastic elasticity elastin enhanced enzyme expansion extent extrinsic facials factors ferulic fiber fibres findings firm firmness formulation full fullness generally gernetic give glycosaminoglycans greater healthy help high however important includes increase increasing inherently injury insult intrinsic lasting less lesser long loss lung marketing massage matrix mature mechanical minimum molecular movement optimal original orphan peptidases protection providing quality quantity skin subject taut zinc

Elastase: The Unrestrained Thief of Skin Elasticity

In molecular biology, elastase is an enzyme from the class of proteases, or peptidases, that break down the protein elastin, an elastic fiber that, together with collagen, determines the mechanical properties of connective tissue, providing skin which is firm, full and taut to a greater or lesser degree depending on its quality and quantity.

Elastin is also an important constituent of lung and vein tissues where, as in the skin, it is subject to repeat expansion and contraction.

The primary structural components of the dermal matrix are collagen fibres, elastin fibres and glycosaminoglycans.

All three of these decrease and deteriorate in quality and quantity due to intrinsic and avoidable extrinsic factors to give the appearance of "aging."

Although rarely used to optimal effect, an array of stimulants and protectants of collagen, and to a far lesser extent, glycosaminoglycans are available. [Refer Mature Skin Analysis — Firmness and Elasticity of Healthy vs. Unhealthy Mature Skin.]

Elastin remains an orphan, with no widely available solutions for its protection or replacement.

Accordingly, while you may potentially increase your skin's volume to give it an appearance of greater fullness, you cannot regain its ability to recoil and remain inherently taut as it was in youth.

As if to add insult to injury, elastin production more or less stops by the end of the teenage years, long before most will consider its protection.

Some findings suggest zinc may benefit elastin, however useful forms and concentrations of zinc are absent from most skincare.

Recently, zinc sulphate was removed from the revised Skinceuticals C E Ferulic Formulation although marketing communicates generally enhanced skin protection when compared with the original C + E Formulation.

Unfortunately both very low and very high concentrations of zinc have been seen to increase elastase activity (increasing the rate of elastin breakdown), such topical and systemic zinc supplementation is problematic.

Thiotaine and a chemical compound found in Gernetic Anti-Radical Eye Gel may help prevent elastase activity.

To avoid loss of high quality elastin, at minimum don't smoke, always confer optimal photoprotection for your skin and avoid rough or unnecessary treatment — this includes facials with massage which subject the skin to movement while providing no considerable or lasting benefit.

Related Skin Care Information, Products and Expert Discussions

Antioxidants

More About Free Radicals

Collagen

Elastin

Dermal Collagen

Skin Care and Dermatological Glossary :

Phospholipids : Alcohols : Dietary Antioxidants : Glycolic Acid : Rosacea : ATP : About Trehalose : Accutane (Isotretinoin) : Acidic : Actinic : Alkaline : Alopecia : Amino Acids : Amphoteric : Angiogenesis : Angioma : Antioxidants : Aqueous : Arc : Arteriole : Artery : Ascorbic Acid / Vitamin C : Atherogenic : Atopic : Benzene : Bioavailability : Bioflavonoid : Biopsy : Biotechnology : Blackhead : Cadaver : Calcium : Capillary : Carboxyl : Carcinogenicity : Carcinoma : Cartilage : Catechins : Cell Division : Cellulitis : Chromatography : Cicatrix : Citric Acid : Citronellol : Coccidioidomycosis : Colitis : Collagen : Colourimetre : Comedo/Comedone : Compound : Connective Tissue : Contusion : Corpus Luteum : Cosmesis : Cyst : Cytochrome : Cytotoxin : Denature : Dermatitis : Dermis : Diabetes : Dibasic Acid : Diploidy/Diploid : Diuretic : Eczema : Edema/Oedema : Elastase: The Unrestrained Thief of Skin Elasticity : Elastin : Electrolysis : Electrophoresis : Emollient : Enantiomer : Endothelium : Environmental Stressors : Enzymes : Eosin : Epidermal Necrosis : Epidermis : Epithelium : Erythema : Essential Fatty Acids : Essential Oils : Esters : Eugenol : Eukaryote/Eukaryotic : Exanthem/Exanthema : Extirpation : Fatty Acids : Ferulic Acid : Fibroblast : Flavonolignan : Flora : Folic Acid (Pteroylglutamic Acid/Vitamin M) : Follicle : Free Radical : Fullerene : Galapagos Tortoise : Gamete : Gene : Genistein : Genome : Genomic DNA : Genotoxin : Glasswort : Glucagon : Glutamic Acid : Glycation : Glycerin : Glycopeptide : Glycoprotein : Glycosaminoglycans : Haploidy/Haploid : Hematoxylin : High Frequency Glass Electrode Beauty Devices : Histology/Histologic : Hives : Hormone : Humectant : Hyaluronic Acid/Sodium Hyaluronate : Hydrocarbon : Hydrolysis : Hydrophilic : Hydrophobic : Hydroxyl (OH) : Hygroscopic : Hypertrophic Scar : Hypochlorous Acid : Hypopigmentation : Immunosuppression : In Summary: Oxidation/Reduction and Tanning : In Vitro : In Vivo : Insulin : Interleukins : Ischemia : Islet : Islets of Langerhans/Islands of Langerhans : Isoprene : Keloid : Keratin : Keratinocytes : Kinase : Lactic Acid : Lactoferrin : Lignin : Limonene : Lipids : Lipophilic : Lymphatic System : MMPs (Matrix Metalloproteinases) : Macromolecule : Malic Acid : Mandelic Acid : Melanin : Melanoma : Membrane : Membrane : Mermaid : Metabolism : Metalloproteinases : Metastatic : Methionine : Micellization : Microtubule : Mineral : Molecular/Cellular Biology: Skin Functioning at the most Essential Level : Molecule : Moles (Blemishes)/Moles Per Litre : Monomer : Mucin : Mucoproteins : Myelin : Nanotechnology : Neurotoxin : Nitrogen : Nodule : Nymph : ORAC : Occlusive : Optic : Otorhinolaryngology : Oxygen : Oxytalan Fibers/Fibres : Ozone : Palmitic Acid : Papain : Papillary Dermis : Papule : Pentacyclic : Pentapeptides GM and GD : Pentose : Peptidases : Peptides : Perichondrium : Peroxidase : Peroxide : Phenol : Phlebitis : Photosensitivity : Phytostimulines : Pigmentation : Pimple : Pledget : Polymer : Polymer/Polymeric : Polypeptide : Polyquaterium-51 : Post-Inflammatory Hyperpigmentation : Pro-Collagen : Prodrug : Proenzymes : Prophylaxis : Propionibacterium / P. Acnes Bacteria : Proteases : Protein : Proteoglycans : Proteolytic Enzymes : Proteome : Pruritus : Psoriasis : Pure/Purity : Pustule : Radiation : Radical : Redox : Reductase : Reperfusion : Restenosis : Reticular Dermis : Retinol : Rhinoplasty : Rockfish : Saccharides : Sebum : Selenium (Definition) : Selenosis : Senescence : Sentinel : Skin Resurfacing by Laser : Skin Structure Diagram : Sodium PCA : Squamous : Stable/Stability : Stenosis : Stratum Corneum : Subclinical Inflammation : Subcutis : Sulfur : Surfactant : Synovial : Tannins : Tartaric Acid : Telomere : Temporal Bones : Thermoregulation / Thermoregulate : Thymine Dimer : Tocopherol : Transferase : Tribasic Acid : Triterpenoid : Tropoelastin : Tubulin : Ubiquinone — Co-Enzyme Q-10 : Vascular : Vascular Epithelial Growth Factor : Vein : Venule : Vestibule : Viscous : Vitamin K : Vitamin PP/Nicotinate : Vitamins : Whitehead : Xerosis : Zygoma : Zygote : pH :

File Elastase: The Unrestrained Thief of Skin Elasticity for reference.

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Elastase: The Unrestrained Thief of Skin Elasticity


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	Elastase: The Unrestrained Thief of Skin Elasticity In molecular biology, elastase is an enzyme from the class of proteases, or peptidases, that break down the protein elastin, an elastic fiber that, together with collagen, determines the mechanical properties of connective tissue, providing skin which is firm, full and taut to a greater or lesser degree depending on its quality and quantity. Elastin is also an important constituent of lung and vein tissues where, as in the skin, it is subject to repeat expansion and contraction. The primary structural components of the dermal matrix are collagen fibres, elastin fibres and glycosaminoglycans. All three of these decrease and deteriorate in quality and quantity due to intrinsic and avoidable extrinsic factors to give the appearance of "aging." Although rarely used to optimal effect, an array of stimulants and protectants of collagen, and to a far lesser extent, glycosaminoglycans are available. [Refer Mature Skin Analysis — Firmness and Elasticity of Healthy vs. Unhealthy Mature Skin.] Elastin remains an orphan, with no widely available solutions for its protection or replacement. Accordingly, while you may potentially increase your skin's volume to give it an appearance of greater fullness, you cannot regain its ability to recoil and remain inherently taut as it was in youth. As if to add insult to injury, elastin production more or less stops by the end of the teenage years, long before most will consider its protection. Some findings suggest zinc may benefit elastin, however useful forms and concentrations of zinc are absent from most skincare. Recently, zinc sulphate was removed from the revised Skinceuticals C E Ferulic Formulation although marketing communicates generally enhanced skin protection when compared with the original C + E Formulation. Unfortunately both very low and very high concentrations of zinc have been seen to increase elastase activity (increasing the rate of elastin breakdown), such topical and systemic zinc supplementation is problematic. Thiotaine and a chemical compound found in Gernetic Anti-Radical Eye Gel may help prevent elastase activity. To avoid loss of high quality elastin, at minimum don't smoke, always confer optimal photoprotection for your skin and avoid rough or unnecessary treatment — this includes facials with massage which subject the skin to movement while providing no considerable or lasting benefit. Skin Care and Dermatological Glossary : Phospholipids : Alcohols : Dietary Antioxidants : Glycolic Acid : Rosacea : ATP : About Trehalose : Accutane (Isotretinoin) : Acidic : Actinic : Alkaline : Alopecia : Amino Acids : Amphoteric : Angiogenesis : Angioma : Antioxidants : Aqueous : Arc : Arteriole : Artery : Ascorbic Acid / Vitamin C : Atherogenic : Atopic : Benzene : Bioavailability : Bioflavonoid : Biopsy : Biotechnology : Blackhead : Cadaver : Calcium : Capillary : Carboxyl : Carcinogenicity : Carcinoma : Cartilage : Catechins : Cell Division : Cellulitis : Chromatography : Cicatrix : Citric Acid : Citronellol : Coccidioidomycosis : Colitis : Collagen : Colourimetre : Comedo/Comedone : Compound : Connective Tissue : Contusion : Corpus Luteum : Cosmesis : Cyst : Cytochrome : Cytotoxin : Denature : Dermatitis : Dermis : Diabetes : Dibasic Acid : Diploidy/Diploid : Diuretic : Eczema : Edema/Oedema : Elastase: The Unrestrained Thief of Skin Elasticity : Elastin : Electrolysis : Electrophoresis : Emollient : Enantiomer : Endothelium : Environmental Stressors : Enzymes : Eosin : Epidermal Necrosis : Epidermis : Epithelium : Erythema : Essential Fatty Acids : Essential Oils : Esters : Eugenol : Eukaryote/Eukaryotic : Exanthem/Exanthema : Extirpation : Fatty Acids : Ferulic Acid : Fibroblast : Flavonolignan : Flora : Folic Acid (Pteroylglutamic Acid/Vitamin M) : Follicle : Free Radical : Fullerene : Galapagos Tortoise : Gamete : Gene : Genistein : Genome : Genomic DNA : Genotoxin : Glasswort : Glucagon : Glutamic Acid : Glycation : Glycerin : Glycopeptide : Glycoprotein : Glycosaminoglycans : Haploidy/Haploid : Hematoxylin : High Frequency Glass Electrode Beauty Devices : Histology/Histologic : Hives : Hormone : Humectant : Hyaluronic Acid/Sodium Hyaluronate : Hydrocarbon : Hydrolysis : Hydrophilic : Hydrophobic : Hydroxyl (OH) : Hygroscopic : Hypertrophic Scar : Hypochlorous Acid : Hypopigmentation : Immunosuppression : In Summary: Oxidation/Reduction and Tanning : In Vitro : In Vivo : Insulin : Interleukins : Ischemia : Islet : Islets of Langerhans/Islands of Langerhans : Isoprene : Keloid : Keratin : Keratinocytes : Kinase : Lactic Acid : Lactoferrin : Lignin : Limonene : Lipids : Lipophilic : Lymphatic System : MMPs (Matrix Metalloproteinases) : Macromolecule : Malic Acid : Mandelic Acid : Melanin : Melanoma : Membrane : Membrane : Mermaid : Metabolism : Metalloproteinases : Metastatic : Methionine : Micellization : Microtubule : Mineral : Molecular/Cellular Biology: Skin Functioning at the most Essential Level : Molecule : Moles (Blemishes)/Moles Per Litre : Monomer : Mucin : Mucoproteins : Myelin : Nanotechnology : Neurotoxin : Nitrogen : Nodule : Nymph : ORAC : Occlusive : Optic : Otorhinolaryngology : Oxygen : Oxytalan Fibers/Fibres : Ozone : Palmitic Acid : Papain : Papillary Dermis : Papule : Pentacyclic : Pentapeptides GM and GD : Pentose : Peptidases : Peptides : Perichondrium : Peroxidase : Peroxide : Phenol : Phlebitis : Photosensitivity : Phytostimulines : Pigmentation : Pimple : Pledget : Polymer : Polymer/Polymeric : Polypeptide : Polyquaterium-51 : Post-Inflammatory Hyperpigmentation : Pro-Collagen : Prodrug : Proenzymes : Prophylaxis : Propionibacterium / P. Acnes Bacteria : Proteases : Protein : Proteoglycans : Proteolytic Enzymes : Proteome : Pruritus : Psoriasis : Pure/Purity : Pustule : Radiation : Radical : Redox : Reductase : Reperfusion : Restenosis : Reticular Dermis : Retinol : Rhinoplasty : Rockfish : Saccharides : Sebum : Selenium (Definition) : Selenosis : Senescence : Sentinel : Skin Resurfacing by Laser : Skin Structure Diagram : Sodium PCA : Squamous : Stable/Stability : Stenosis : Stratum Corneum : Subclinical Inflammation : Subcutis : Sulfur : Surfactant : Synovial : Tannins : Tartaric Acid : Telomere : Temporal Bones : Thermoregulation / Thermoregulate : Thymine Dimer : Tocopherol : Transferase : Tribasic Acid : Triterpenoid : Tropoelastin : Tubulin : Ubiquinone — Co-Enzyme Q-10 : Vascular : Vascular Epithelial Growth Factor : Vein : Venule : Vestibule : Viscous : Vitamin K : Vitamin PP/Nicotinate : Vitamins : Whitehead : Xerosis : Zygoma : Zygote : pH : Related Skin Care Information, Products and Expert Discussions Antioxidants More About Free Radicals Collagen Elastin Dermal Collagen Skin Care and Dermatological Glossary : Phospholipids : Alcohols : Dietary Antioxidants : Glycolic Acid : Rosacea : ATP : About Trehalose : Accutane (Isotretinoin) : Acidic : Actinic : Alkaline : Alopecia : Amino Acids : Amphoteric : Angiogenesis : Angioma : Antioxidants : Aqueous : Arc : Arteriole : Artery : Ascorbic Acid / Vitamin C : Atherogenic : Atopic : Benzene : Bioavailability : Bioflavonoid : Biopsy : Biotechnology : Blackhead : Cadaver : Calcium : Capillary : Carboxyl : Carcinogenicity : Carcinoma : Cartilage : Catechins : Cell Division : Cellulitis : Chromatography : Cicatrix : Citric Acid : Citronellol : Coccidioidomycosis : Colitis : Collagen : Colourimetre : Comedo/Comedone : Compound : Connective Tissue : Contusion : Corpus Luteum : Cosmesis : Cyst : Cytochrome : Cytotoxin : Denature : Dermatitis : Dermis : Diabetes : Dibasic Acid : Diploidy/Diploid : Diuretic : Eczema : Edema/Oedema : Elastase: The Unrestrained Thief of Skin Elasticity : Elastin : Electrolysis : Electrophoresis : Emollient : Enantiomer : Endothelium : Environmental Stressors : Enzymes : Eosin : Epidermal Necrosis : Epidermis : Epithelium : Erythema : Essential Fatty Acids : Essential Oils : Esters : Eugenol : Eukaryote/Eukaryotic : Exanthem/Exanthema : Extirpation : Fatty Acids : Ferulic Acid : Fibroblast : Flavonolignan : Flora : Folic Acid (Pteroylglutamic Acid/Vitamin M) : Follicle : Free Radical : Fullerene : Galapagos Tortoise : Gamete : Gene : Genistein : Genome : Genomic DNA : Genotoxin : Glasswort : Glucagon : Glutamic Acid : Glycation : Glycerin : Glycopeptide : Glycoprotein : Glycosaminoglycans : Haploidy/Haploid : Hematoxylin : High Frequency Glass Electrode Beauty Devices : Histology/Histologic : Hives : Hormone : Humectant : Hyaluronic Acid/Sodium Hyaluronate : Hydrocarbon : Hydrolysis : Hydrophilic : Hydrophobic : Hydroxyl (OH) : Hygroscopic : Hypertrophic Scar : Hypochlorous Acid : Hypopigmentation : Immunosuppression : In Summary: Oxidation/Reduction and Tanning : In Vitro : In Vivo : Insulin : Interleukins : Ischemia : Islet : Islets of Langerhans/Islands of Langerhans : Isoprene : Keloid : Keratin : Keratinocytes : Kinase : Lactic Acid : Lactoferrin : Lignin : Limonene : Lipids : Lipophilic : Lymphatic System : MMPs (Matrix Metalloproteinases) : Macromolecule : Malic Acid : Mandelic Acid : Melanin : Melanoma : Membrane : Membrane : Mermaid : Metabolism : Metalloproteinases : Metastatic : Methionine : Micellization : Microtubule : Mineral : Molecular/Cellular Biology: Skin Functioning at the most Essential Level : Molecule : Moles (Blemishes)/Moles Per Litre : Monomer : Mucin : Mucoproteins : Myelin : Nanotechnology : Neurotoxin : Nitrogen : Nodule : Nymph : ORAC : Occlusive : Optic : Otorhinolaryngology : Oxygen : Oxytalan Fibers/Fibres : Ozone : Palmitic Acid : Papain : Papillary Dermis : Papule : Pentacyclic : Pentapeptides GM and GD : Pentose : Peptidases : Peptides : Perichondrium : Peroxidase : Peroxide : Phenol : Phlebitis : Photosensitivity : Phytostimulines : Pigmentation : Pimple : Pledget : Polymer : Polymer/Polymeric : Polypeptide : Polyquaterium-51 : Post-Inflammatory Hyperpigmentation : Pro-Collagen : Prodrug : Proenzymes : Prophylaxis : Propionibacterium / P. Acnes Bacteria : Proteases : Protein : Proteoglycans : Proteolytic Enzymes : Proteome : Pruritus : Psoriasis : Pure/Purity : Pustule : Radiation : Radical : Redox : Reductase : Reperfusion : Restenosis : Reticular Dermis : Retinol : Rhinoplasty : Rockfish : Saccharides : Sebum : Selenium (Definition) : Selenosis : Senescence : Sentinel : Skin Resurfacing by Laser : Skin Structure Diagram : Sodium PCA : Squamous : Stable/Stability : Stenosis : Stratum Corneum : Subclinical Inflammation : Subcutis : Sulfur : Surfactant : Synovial : Tannins : Tartaric Acid : Telomere : Temporal Bones : Thermoregulation / Thermoregulate : Thymine Dimer : Tocopherol : Transferase : Tribasic Acid : Triterpenoid : Tropoelastin : Tubulin : Ubiquinone — Co-Enzyme Q-10 : Vascular : Vascular Epithelial Growth Factor : Vein : Venule : Vestibule : Viscous : Vitamin K : Vitamin PP/Nicotinate : Vitamins : Whitehead : Xerosis : Zygoma : Zygote : pH : File Elastase: The Unrestrained Thief of Skin Elasticity for reference.	August 2010 Special Preparation / Special Order Items July 2010 SkinMedica Chemical Peels Nia24 Reference Manual June 2010 New Anthelios 45 Sunscreens for Face and Body Replenix Anti-Photoaging Sunscreen SPF 45 VitaMedica HA + A Program May 2010 New Skinceuticals Sheer Physical UV Defense SPF 50 Alyria Antioxidant Capsules (Vitamin C + E) IS Clinical Youth Complex April 2010 RevaleSkin — CoffeeBerry Extract Retin-A Gel Availability March 2010 RevaleSkin Day Cream SPF 15 Trehalose February 2010 Injuv Polyphenols Kinerase Pro+ C8 Peptide Intensive Treatment with Kinetin and Zeatin January 2010 La Roche-Posay Redermic December 2009 Anti-Aging Sunscreen Reminders November 2009 Complimentary Shipping The Sun Zinc: An Important Antioxidant for Skin La Roche-Posay Derm AOX Biomedic Potent-C 10.5 Concentrate Tocotrienols Skinceuticals Pigment Regulator SkinMedica Retinol Complex October 2009 The Connection Between Oxidative Stress and Aging Definition of Oxidative Stress Sources of Free Radical Damage Ozone Obagi Professional C Ingredients Citrix Antioxidant Body Lotion September 2009 Tricomin Erythema from Retinoids Carnosine Interleukin-6 (IL-6) Asiaticoside vs. Madecassoside for Collagen Synthesis New Elta MD UV Clear SPF 46 New DCL Super Sheer Sunscreen SPF 50+ PCA pHaze 16+ C-Strength 20% Arginine and Serine Chrysin August 2009 Glytone Lipo-Lift Serum Ergothioneine Ubiquinone (Co-Enzyme Q-10) Tetrahexyldecyl Ascorbate Hydrolyzed Hyaluronic Acid Polymorphous Light Eruption Saccharomyces Ferment (Filtrate Lysate) La Roche-Posay Effaclar AI Intensive Acne Spot Treatment New Skinceuticals Retexturing Activator New Vivite Defining Lip Plumper Neova Advanced Essential Lash July 2009 Ceramide 3 Oxido Reductases Cellex-C vs. Skinceuticals D-Tocopheryl Glucoside Human Fibroblast Conditioned Media Kinerase Pro+ Therapy Advanced Radiance Facial Peel June 2009 Pentapeptides Ineffective ReVivé Peau Magnifique Madecassoside Natural/Organic Instinct Products Contain Unlisted + Mislabelled Chemicals Neutrogena Amber Bar Sculpture La Roche-Posay, Vienne, France Obagi Rosaclear May 2009 Myristyl Nicotinate Topical Myristyl Nicotinate Creams Oxofulleram Benefits of Mexoryl SX Anthelios 60 Sunscreens Anthelios SX Daily Moisturizer RevaleSkin CoffeeBerry Kit April 2009 Biomedic Facial Shield SPF 20 IS Clinical Peptides Skin Care for Dry Body Skin Site Upgrades and Updates March 2009 Safety of Micronized Zinc Sunscreens Kinetin RevaleSkin — CoffeeBerry Extract Glycation Biomedic Collagenist Powder p53 Protein Expression Photoprotective (UVB) Salen-Manganese Complex (EUK-134) Clinique Medical Skin Care (Newly Available)