65,000+ expert documents for the skincare aficionado.
Home
Login
View Cart/Checkout
Contact/Customer Service
Perennial / Wisdoms
UV Exposure
Aging Skin and Mature Skin
Theories of Aging
Skin Care
Afirm RetinolAllergan
Alyria
Anthelios
Avene
B. Kamins
Biomedic
Blue Lizard
Cellex-C
Cetaphil
Citrix
Clarisonic
Colorescience
Combray
Cotz
Clinique Medical
DCL
Dermatix
Elastiderm
Elta MD
Estion
Ethocyn
Exuviance
Fake Bake
Glycolix
Glyderm
Glytone
Great Lips Rx
Heliocare
IS Clinical
Kinerase
Kinerase Clear
Kinerase Pro+
La Prairie
La Roche Posay
L-M-X
MD Lash Factor
MD Rx
Neoceuticals
Neocutis
Neostrata
Neova
Nia24
Nordic Naturals
Obagi
Obagi Rosaclear
Obagi Rx
OC Eight
Olos
PCA Skin
Pentaxyl
Prevage MD
Priori
Phytomer
Remergent
Replenix
RevaleSkin
Revision
Revitalash MD
Scarguard
SesDerma
Skinceuticals
SkinMedica
SunSpot
Teamine
Theraplex
Ti-Silc / Z-Silc
TNS
Topix
Tricomin
VitaMedica
Zeno MD
Browse more brands.
Product Types
Facial Cleansers
Antioxidants
Moisturizers
Sunscreens
Retinoids
Shampoos
Facial Skin Condition Treatments
Adult Acne
Broken Capillaries
Dark Circles
Deep Wrinkles
Dry Skin
Eyelid Toning
Fine Lines
Hyperpigmentation
Lips
Open Pores
Puffy Eyes
Rosacea
Body Skin Condition Treatments
Aging Hands
Breast Firming
Cellulite
Ingrown Hairs
Keratosis Pilaris
Scalp Acne
Stretch Marks
Skin Care Ingredients
Alpha Hydroxy Acids (AHAs)Betaglucans
Bimatoprost
Centella Asiatica
Coffee Berry
Ferulic Acid
Glutathione
Mexoryl
Nymphae Alba
Peroxidase
Phloretin
Silymarin
Sodium Laureth Sulfate/Sulphate
Superoxide Dismutase
Telomerase
Vitamin E
Browse more ingredients.
Clinical Procedures and Topics
Four Fundamentals
Absurd Skin Care
Aging Skin
Antioxidants
Botox
Enzyme Exfoliation
Free Radical Damage
French Skin Care
Glycolic Acid
Idebenone
Irrational Fears
Klein Becker
Oxidative Stress
Paula Begoun
Perricone
Restylane
Skin Structure
Stem Cells
Healthy Skin Barrier Function
Smoking
Sun Protection
Topical Vitamin C/Firming
Choices and Needs
Strivectin
Additional clinical skincare topics.
Fibroblast
A fibroblast is a cell in connective tissue that produces collagen and other fibres.
Fibroblasts are interspersed among the collagen fibers of the dermis, and synthesize collagen and the ground substance of the dermis (glycosaminoglycans).
The fibroblasts are more numerous and larger in the papillary dermis than in the reticular dermis.
Why do skin fibroblasts slow down their collagen production as we get older, even though they can still produce it?
Fibroblasts in aged tissue start acting old themselves.
When fibroblasts are isolated from aged tissue in the lab and exposed to the same stimulating factors the body uses to kick them into gear, skin fibroblasts once again start producing significant quantities of collagen.
Skin Care and Dermatological Glossary :
Phospholipids : Alcohols : Dietary Antioxidants : Glycolic Acid : Rosacea : ATP : About Trehalose : Accutane (Isotretinoin) : Acidic : Actinic : Alkaline : Alopecia : Amino Acids : Angiogenesis : Angioma : Antioxidants : Aqueous : Arc : Arteriole : Artery : Ascorbic Acid / Vitamin C : Atherogenic : Atopic : Benzene : Bioavailability : Bioflavonoid : Biopsy : Biotechnology : Blackhead : Cadaver : Calcium : Capillary : Carboxyl : Carcinogenicity : Carcinoma : Cartilage : Catechins : Cell Division : Cellulitis : Chromatography : Cicatrix : Citric Acid : Citronellol : Coccidioidomycosis : Colitis : Collagen : Colourimetre : Comedo/Comedone : Compound : Connective Tissue : Contusion : Corpus Luteum : Cosmesis : Cyst : Cytochrome : Cytotoxin : Denature : Dermatitis : Dermis : Diabetes : Dibasic Acid : Diploidy/Diploid : Eczema : Edema/Oedema : Elastase: The Unrestrained Thief of Skin Elasticity : Elastin : Electrolysis : Electrophoresis : Emollient : Enantiomer : Endothelium : Environmental Stressors : Enzymes : Eosin : Epidermal Necrosis : Epidermis : Epithelium : Erythema : Essential Fatty Acids : Essential Oils : Esters : Eugenol : Eukaryote/Eukaryotic : Exanthem/Exanthema : Extirpation : Fatty Acids : Ferulic Acid : Fibroblast : Flavonolignan : Flora : Folic Acid (Pteroylglutamic Acid/Vitamin M) : Follicle : Free Radical : Fullerene : Galapagos Tortoise : Gamete : Gene : Genistein : Genome : Genomic DNA : Genotoxin : Glasswort : Glucagon : Glutamic Acid : Glycation : Glycerin : Glycopeptide : Glycoprotein : Glycosaminoglycans : Haploidy/Haploid : Hematoxylin : High Frequency Glass Electrode Beauty Devices : Histology/Histologic : Hives : Hormone : Humectant : Hyaluronic Acid/Sodium Hyaluronate : Hydrocarbon : Hydrolysis : Hydrophilic : Hydrophobic : Hydroxyl (OH) : Hygroscopic : Hypertrophic Scar : Hypochlorous Acid : Hypopigmentation : Immunosuppression : In Summary: Oxidation/Reduction and Tanning : In Vitro : In Vivo : Insulin : Interleukins : Ischemia : Islet : Islets of Langerhans/Islands of Langerhans : Isoprene : Keloid : Keratin : Keratinocytes : Kinase : Lactic Acid : Lactoferrin : Lignin : Limonene : Lipids : Lipophilic : Lymphatic System : MMPs (Matrix Metalloproteinases) : Macromolecule : Malic Acid : Mandelic Acid : Melanin : Melanoma : Membrane : Membrane : Mermaid : Metabolism : Metalloproteinases : Metastatic : Methionine : Micellization : Microtubule : Mineral : Molecular/Cellular Biology: Skin Functioning at the most Essential Level : Molecule : Moles (Blemishes)/Moles Per Litre : Monomer : Mucin : Mucoproteins : Myelin : Nanotechnology : Neurotoxin : Nitrogen : Nodule : Nymph : ORAC : Occlusive : Optic : Otorhinolaryngology : Oxygen : Oxytalan Fibers/Fibres : Ozone : Palmitic Acid : Papain : Papillary Dermis : Papule : Pentacyclic : Pentapeptides GM and GD : Pentose : Peptidases : Peptides : Perichondrium : Peroxidase : Peroxide : Phenol : Phlebitis : Photosensitivity : Phytostimulines : Pigmentation : Pimple : Pledget : Polymer : Polymer/Polymeric : Polypeptide : Polyquaterium-51 : Post-Inflammatory Hyperpigmentation : Pro-Collagen : Prodrug : Proenzymes : Prophylaxis : Propionibacterium / P. Acnes Bacteria : Proteases : Protein : Proteoglycans : Proteolytic Enzymes : Proteome : Pruritus : Psoriasis : Pure/Purity : Pustule : Radiation : Radical : Redox : Reductase : Reperfusion : Restenosis : Reticular Dermis : Retinol : Rhinoplasty : Rockfish : Saccharides : Sebum : Selenium (Definition) : Selenosis : Senescence : Sentinel : Skin Resurfacing by Laser : Skin Structure Diagram : Sodium PCA : Squamous : Stable/Stability : Stenosis : Stratum Corneum : Subclinical Inflammation : Subcutis : Sulfur : Surfactant : Synovial : Tannins : Tartaric Acid : Telomere : Temporal Bones : Thermoregulation / Thermoregulate : Thymine Dimer : Tocopherol : Transferase : Tribasic Acid : Triterpenoid : Tropoelastin : Tubulin : Ubiquinone — Co-Enzyme Q-10 : Vascular : Vascular Epithelial Growth Factor : Vein : Venule : Vestibule : Viscous : Vitamin K : Vitamin PP/Nicotinate : Vitamins : Whitehead : Xerosis : Zygoma : Zygote : pH :
Related Skin Care Information, Products and Expert Discussions
Skin Care and Dermatological Glossary :
Phospholipids : Alcohols : Dietary Antioxidants : Glycolic Acid : Rosacea : ATP : About Trehalose : Accutane (Isotretinoin) : Acidic : Actinic : Alkaline : Alopecia : Amino Acids : Angiogenesis : Angioma : Antioxidants : Aqueous : Arc : Arteriole : Artery : Ascorbic Acid / Vitamin C : Atherogenic : Atopic : Benzene : Bioavailability : Bioflavonoid : Biopsy : Biotechnology : Blackhead : Cadaver : Calcium : Capillary : Carboxyl : Carcinogenicity : Carcinoma : Cartilage : Catechins : Cell Division : Cellulitis : Chromatography : Cicatrix : Citric Acid : Citronellol : Coccidioidomycosis : Colitis : Collagen : Colourimetre : Comedo/Comedone : Compound : Connective Tissue : Contusion : Corpus Luteum : Cosmesis : Cyst : Cytochrome : Cytotoxin : Denature : Dermatitis : Dermis : Diabetes : Dibasic Acid : Diploidy/Diploid : Eczema : Edema/Oedema : Elastase: The Unrestrained Thief of Skin Elasticity : Elastin : Electrolysis : Electrophoresis : Emollient : Enantiomer : Endothelium : Environmental Stressors : Enzymes : Eosin : Epidermal Necrosis : Epidermis : Epithelium : Erythema : Essential Fatty Acids : Essential Oils : Esters : Eugenol : Eukaryote/Eukaryotic : Exanthem/Exanthema : Extirpation : Fatty Acids : Ferulic Acid : Fibroblast : Flavonolignan : Flora : Folic Acid (Pteroylglutamic Acid/Vitamin M) : Follicle : Free Radical : Fullerene : Galapagos Tortoise : Gamete : Gene : Genistein : Genome : Genomic DNA : Genotoxin : Glasswort : Glucagon : Glutamic Acid : Glycation : Glycerin : Glycopeptide : Glycoprotein : Glycosaminoglycans : Haploidy/Haploid : Hematoxylin : High Frequency Glass Electrode Beauty Devices : Histology/Histologic : Hives : Hormone : Humectant : Hyaluronic Acid/Sodium Hyaluronate : Hydrocarbon : Hydrolysis : Hydrophilic : Hydrophobic : Hydroxyl (OH) : Hygroscopic : Hypertrophic Scar : Hypochlorous Acid : Hypopigmentation : Immunosuppression : In Summary: Oxidation/Reduction and Tanning : In Vitro : In Vivo : Insulin : Interleukins : Ischemia : Islet : Islets of Langerhans/Islands of Langerhans : Isoprene : Keloid : Keratin : Keratinocytes : Kinase : Lactic Acid : Lactoferrin : Lignin : Limonene : Lipids : Lipophilic : Lymphatic System : MMPs (Matrix Metalloproteinases) : Macromolecule : Malic Acid : Mandelic Acid : Melanin : Melanoma : Membrane : Membrane : Mermaid : Metabolism : Metalloproteinases : Metastatic : Methionine : Micellization : Microtubule : Mineral : Molecular/Cellular Biology: Skin Functioning at the most Essential Level : Molecule : Moles (Blemishes)/Moles Per Litre : Monomer : Mucin : Mucoproteins : Myelin : Nanotechnology : Neurotoxin : Nitrogen : Nodule : Nymph : ORAC : Occlusive : Optic : Otorhinolaryngology : Oxygen : Oxytalan Fibers/Fibres : Ozone : Palmitic Acid : Papain : Papillary Dermis : Papule : Pentacyclic : Pentapeptides GM and GD : Pentose : Peptidases : Peptides : Perichondrium : Peroxidase : Peroxide : Phenol : Phlebitis : Photosensitivity : Phytostimulines : Pigmentation : Pimple : Pledget : Polymer : Polymer/Polymeric : Polypeptide : Polyquaterium-51 : Post-Inflammatory Hyperpigmentation : Pro-Collagen : Prodrug : Proenzymes : Prophylaxis : Propionibacterium / P. Acnes Bacteria : Proteases : Protein : Proteoglycans : Proteolytic Enzymes : Proteome : Pruritus : Psoriasis : Pure/Purity : Pustule : Radiation : Radical : Redox : Reductase : Reperfusion : Restenosis : Reticular Dermis : Retinol : Rhinoplasty : Rockfish : Saccharides : Sebum : Selenium (Definition) : Selenosis : Senescence : Sentinel : Skin Resurfacing by Laser : Skin Structure Diagram : Sodium PCA : Squamous : Stable/Stability : Stenosis : Stratum Corneum : Subclinical Inflammation : Subcutis : Sulfur : Surfactant : Synovial : Tannins : Tartaric Acid : Telomere : Temporal Bones : Thermoregulation / Thermoregulate : Thymine Dimer : Tocopherol : Transferase : Tribasic Acid : Triterpenoid : Tropoelastin : Tubulin : Ubiquinone — Co-Enzyme Q-10 : Vascular : Vascular Epithelial Growth Factor : Vein : Venule : Vestibule : Viscous : Vitamin K : Vitamin PP/Nicotinate : Vitamins : Whitehead : Xerosis : Zygoma : Zygote : pH :
June 2009
Natural/Organic Instinct Products Contain Unlisted + Mislabelled Chemicals
Neutrogena Amber Bar Sculpture
May 2009
April 2009
March 2009
Safety of Micronized Zinc Sunscreens
RevaleSkin — CoffeeBerry Extract
February 2009
January 2009
December 2008
Oxidative Stress/Damage Theory of Aging Disproven by Study
Safety Concerns Over High-Tech (Nanotechnology) Sunscreens
Why Protect Against UVA Exposure?
Flawed Skin Analogy: The M.D. Formulations Onion
November 2008
New — MD Rx Antioxidant Hair Replenishing Mist
MD Rx Antioxidant Hair Replenishing Mist Ingredients
Algorithm for Optimal Sustained Exfoliation: Glycolic Acid
Tetrahexyldecyl Ascorbate replaces Ascorbyl Palmitate in N.V. Perricone Products
October 2008
Joan Crawford's Deleterious Facial Cleansing Protocol
Cytotoxicity of Lavender Oil and its Major Components to Human Skin Cells
Do Everything At Once / Never Complete A Single Treatment
Beauty Product Consumers like Old Sailors (The Old Sailor, by A. A. Milne)
Hostile Marital Interactions, Proinflammatory Cytokine Production, and Wound Healing
Nicholas Perricone: Sugar is Primarily Responsible for Inflammation
September 2008
New SkinCeuticals A.G.E. Interrupter
Induction of Collagen by Topical Estradiol
Sources of Free Radical Damage
The Skin and Free Radical Damage
August 2008
July 2008
RevaleSkin ORAC Antioxidant Comparison
L'Oreal and Nivea Sunscreens Fail to Provide Stated SPFs
New Darphin Vitalprotection SPF 15 Sunscreen
La Prairie Advanced Marine Biology Cream
June 2008
Ascorbic Acid vs. Ascorbyl Palmitate (2008)
Comments from Anne Campoamor regarding Darphin Photoprotection
A New Proposal for Reducing Hyperpigmentation: Jan Marini Age Intervention Enlighten
May 2008
New Marini Lash from Jan Marini (Skin Research)
Vitamin D/Photoprotection and Depression
April 2008
pH Neutral (7.07) Ascorbic Acid Alone/Primarily Fails Skin
Loss of Elastic Fibers Causes Skin Wrinkles (in Sun-Damaged Human Skin)
March 2008
Dry and Aging Hands — Prevention/Treatment/Example Reparative Protocol
La Roche-Posay — Aging Skin Video: Deep Wrinkles, Loss of Firmness
Sodium Laureth Sulfate/Sulphate
Impact of Beauty Therapy on Patients' Skins
Skinceuticals Hydrating B5 Masque — Dehydrated Skin of Any Age/Type
Petasites Fragrans — Winter Heliotrope (Asteracea) Mediterranean
Carcinogenicity of Skinceuticals Retinol / Review of "Truth In Aging"
February 2008
New — Jan Marini Age Intervention Transitions — (Peri)Menopausal Acne
Heritage Eggplants — Queen Victoria Market
Skinceuticals AOX Body Treatment
Login: Jan Marini Age Intervention Eyelash & Hair
Login: Skinceuticals Eye Cream/Antioxidant Lip Repair/Hydrating B5 Masque
2009 | January | February | March | April | May | June | July | August | September | October | November | December
2008 | January | February | March | April | May | June | July | August | September | October | November | December