Skin Care and Treatments of Melbourne Dermatology - Hair

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Hair

Hair

Wednesday, 14 October 2009

Tricomin

Tricomin

Tricomin

Tricomin by ProCyte is based on the FDA-approved Iamin Hydrogel, a form of the antioxidant superoxide dismutase used in wound healing, with a noted side effect of hair growth stimulation.

Superoxide dismutases are endogenous enzymesproteins cofactored with copper, zinc, manganese, iron or nickel — which catalyze the disproportionation of superoxide into oxygen and hydrogen peroxide, forming a vital antioxidant defense for nearly all eukaryotic cells exposed to oxygen.

Experimental studies in mice have shown that increasing cellular production of superoxide dismutase increases lifespan.

This class of enzymes is also found in some skin care products aimed at preventing photodamage and preventing/treating hyperpigmentation (La Prairie Cellular Defense Shield, Vivité Vibrance Therapy, Citrix Antioxidant Body Lotion and SPF 30).

Topical superoxide dismutase has been shown to reduce post-irradiation breast cancer fibrosis.

Another ProCyte product, GraftCyte, comprising a concentrated superoxide dismutase spray and moist dressing, is FDA-approved to prevent transplanted hairs from entering the telogen phase.

The telogen phase is the resting phase of the hair follicle. At any time 10-20% of all hairs are in the telogen phase. The telogen phase lasts for about 100 days on the scalp, and much longer for the eyebrows and eyelashes.

The patented superoxide dismutase found in Tricomin (Alanine/Histidine/Lysine Polypeptide Copper HCI) is a copper peptide marketed for use in the treatment of hair loss and poor hair and scalp quality, and is also found in Neova Advanced Essential Lash, a product marketed for eyelash enhancement.

Tricomin Before and After Results Picture.

A decrease in hair quality and a loss of hair can be due to decreased growth, increased shedding, breakage or the conversion of thick (terminal) hairs to thin (vellus) hairs.

These scenarios can be as a result of medication intake, genetic and hormonal influences (including stress), internal conditions (iron or thyroid deficiency) and skin diseases or conditions (seborrheic dermatitis, atopic dermatitis) which injure the hair follicle.

Copper helps inhibit 5A-Reductase which in turn reduces the formation of DHT (dihydrotestosterone), a cause of hormonal hair loss, and has been shown to stimulate collagen production, a reduction in which has been associated with less well nourished hair bulbs.

Tricomin may be used to help maintain a healthy scalp and hair or in combination with proven hair loss therapies (Propecia, Minoxidil, Aminexil, Proxiphen and Retinoic Acid) with the aim of enhancing results and reducing scalp irritation (itchy scalp) which may occur with the use of topical hair loss medications.

Tricomin Spray

Tricomin Solution Follicle Therapy Spray is used in a manner similar to a leave-in conditioner, applied either to damp or dry hair and scalp. It is the most potent product containing the highest concentration of the Alanine/Histidine/Lysine Polypeptide Copper HCI antioxidant superoxide dismutase in an alcoholic base for deeper penetration.

Tricomin Revitalizing Shampoo and Tricomin Restructuring Conditioner also contain Alanine/Histidine/Lysine Polypeptide Copper HCI in addition to hydrolyzed keratin and may be used in conjunction with Tricomin Solution Follicle Therapy Spray.

Please note that Tricomin Deep Conditioning Treatment does not contain Alanine/Histidine/Lysine Polypeptide Copper HCI.


Tricomin Before and After Picture Source: ProCyte.


Superoxide Dismutase References for Tricomin Summary:

McCord JM, Fridovich I (1988). "Superoxide dismutase: the first twenty years (1968-1988)". Free Radic. Biol. Med. 5 (5-6): 363—9.

Tainer JA, Getzoff ED, Richardson JS, Richardson DC (1983). "Structure and mechanism of copper, zinc superoxide dismutase.". Nature (5940): 284-7.

Li Y, Huang TT, Carlson EJ, Melov S, Ursell PC, Olson JL, Noble LJ, Yoshimura MP, Berger C, Chan PH, Wallace DC, Epstein CJ (December 1995). "Dilated cardiomyopathy and neonatal lethality in mutant mice lacking manganese superoxide dismutase". Nat. Genet. 11 (4): 376—81.

Elchuri S, Oberley TD, Qi W, Eisenstein RS, Jackson Roberts L, Van Remmen H, Epstein CJ, Huang TT (January 2005). "CuZnSOD deficiency leads to persistent and widespread oxidative damage and hepatocarcinogenesis later in life". Oncogene 24 (3): 367—80.

Sentman ML, Granström M, Jakobson H, Reaume A, Basu S, Marklund SL (March 2006). "Phenotypes of mice lacking extracellular superoxide dismutase and copper- and zinc-containing superoxide dismutase". J. Biol. Chem. 281 (11): 6904—9.

Campana F, Zervoudis S, Perdereau B, Gez E, Fourquet A, Badiu C, Tsakiris G, Koulaloglou S (2004). "Topical superoxide dismutase reduces post-irradiation breast cancer fibrosis". J. Cell. Mol. Med. 8 (1): 109—16.

Vozenin-Brotons MC, Sivan V, Gault N, Renard C, Geffrotin C, Delanian S, Lefaix JL, Martin M (January 2001). "Antifibrotic action of Cu/Zn SOD is mediated by TGF-beta1 repression and phenotypic reversion of myofibroblasts". Free Radic. Biol. Med. 30 (1): 30—42.

Tuesday, 25 November 2008

(Photo)Protection of Hair

(Photo)Protection of Hair

Even on a cloudy day, the quality of hair — a kind of skin — deteriorates in the presence of daylight and oxygen, becoming permanently more rough, dry and less naturally glossy.

Combing, brushing and hot air drying are further deleterious actions which roughen, strip and dehydrate, resulting in hair much weaker and duller than it need ever have become.

Bona fide hair care is a cosmetic concern because the appearance of hair downplays the success of cosmetic procedures and ideal skincare.

While shampoos containing silicone and trace quantities of Provitamin B-5 — most popularly Pantene — temporarily smooth-out hair's damaged structure and texture, shampoos containing sodium laureth sulphate and sodium pareth sulphate remove their fleeting benefit with each application while leaching hair's naturally-protective nutrients.

While the skin may be made to renew itself in as little as 3 months (or much sooner where dermatological procedures such as retinoic acid peels are employed), a full head of medium or longer-length hair is a seven year affair.

In reality, the original health of hair as it emerges is greatly reduced within days of mainstream hair-care.

Within weeks, the hair loses the intensity of its original hue, and the lustre of being moist from within.

Despite the massive volume of shampoos, conditioners and various sprays available in supermarkets and hair salons, products barely differ and essentially what is supplied is the following:

  • detergent cleansers (sodium laureth sulphate, sodium pareth sulphate among other sulphates);

  • rudimentary temporary moisturizers/conditioners (predominantly cetyl alcohol) and oils which smooth the hair by coating it, but always at the expense of volume due to their physical weight on the hair;

  • a variety of silicones which smooth hair, but with a tendency to render it with a sterile appearance, particularly if dry or brittle underneath, and which have emerged as an environmental hazard to water-based organisms.

To enhance and protect the original quality of your hair, particularly with the aim of amplifying or matching your facial appearance:

Wednesday, 11 March 2009

Chromaveil Photoprotection for Hair

Chromaveil is a patented broad spectrum ultraviolet (UV) absorber for hair care products.

Chromaveil is a UV absorbing quaternium compound delivering UVA and UVB protection to the hair, preserving the integrity of the hair fiber, with the added bonus of protecting hair color.

Lab tests have shown the ability of Chromaveil to absorb UVA and UVB radiation, maintaining color after UV exposure and maintaining hair strength.

It is available in an easy-to-use liquid that can be incorporated into cold process and hot process formulations, and is stable in low to neutral pH environments.

As a 75 percent active ingredient, formulators can incorporate Chromaveil without high loads of diluents or solvents.

Monday, 22 August 2011

MD Rx Antioxidant Hair Replenishing Mist

MD Rx Antioxidant Hair Replenishing Mist

An unprecedented combination of high-concentration antioxidants, revitalizing nutrients and sunscreen to protect hair against environmental damage, in particular photoaging.

Predominant Benefits

  • Provides a broad spectrum of superior first-tier antioxidants and sunscreen for optimal photoprotection of hair in an easy-to-use spray;

  • Improves the appearance of all hair types, especially frequently-coloured, washed or blow-dried hair, by nourishing, restructuring and smoothing the hair's cuticul;

  • Protects and revitalizes the scalp — beneficial in cases of scalp acne or itchy scalp.

Key Ingredients

  • Vitamin C (Sodium Ascorbyl Phosphate) — primary aqueous photoprotective antioxidant;

  • Vitamin E (Tocopherol Acetate) — primary lipid-soluble photoprotective antioxidant;

  • Ferulic Acid (4-hydroxy-3-methoxycinnamic acid) — presently one of the most significant non-Vitamin supplementary photoprotective antioxidants available;

  • Grape Seed Polyphenolsphotoprotective and antioxidant, helping to stabilize hair structure and elasticity;

  • Green Tea Polyphenolsphotoprotective and antioxidant helping to stabilize hair structure and elasticity;

  • Panthenol — a deep-penetrating oil-free moisturizer which smoothes the hair cuticle for extended periods of time;

  • Sodium PCA — a superior humectant which exists naturally in hair as a moisturizer, reduced by shampooing, drying and environmental exposure;

  • Allantoin — extracted from Comfrey, a soothing antioxidant recognized by the FDA as a cold sore and fever-blister treatment, helps heal, soothe and protect the hair cuticle;

  • Niacinamide — an antioxidant nutrient which strengthens, renews and stimulates hair fibre while hydrating to increase hair's lustre and elasticity;

  • Benzophenone — a sunscreen which protects against aging UVA rays.

  • Sodium Hyaluronate — superior weightless moisturizer, binds to, protects and smoothes hair.
  • Refer the full ingredient listing.

    Further Information

    MD Rx Antioxidant Hair Replenishing Mist

    See photoprotection of hair.

    Instructions for Use

    1. Wash hair with shampoo not containing sodium laureth sulphate and condition if desired.

    2. Towel dry hair and spray with Antioxidant Hair Replenishing Mist.

    Blow dry and apply styling products if desired.

    1. Style hair, and mist over once to finish.

    Usage Notes

    If indoors, may be re-misted every 4-6 hours for enhanced protection, or to refresh the hair's appearance.

    If exposed to UV, re-mist every 2 hours, or after swimming, wear a broad-rimmed hat and/or avoid direct sun.

    Free of preservatives and alcohol.

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    Open Pores — Treatment and Prevention

    MD Rx Melbourne Dermatology Open Pores Overnight Solution

    The Sun

    Radiation

    Mexoryl

    Pentapeptides Ineffective

    Asiaticoside vs. Madecassoside for Collagen Synthesis

    La Roche-Posay Redermic

    Valeant Pharmaceuticals

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    Avena Sativa

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    Aster Family of Plants

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    Oxofulleram

    Salicylic Acid

    Capryloyl Salicylic Acid

    Open Pores

    Phytosphingosine

    Glycerin

    Idebenone

    Ascorbyl Palmitate

    Kojic Acid

    Algorithm for Optimal Sustained Exfoliation: Glycolic Acid

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