Skin Care and Treatments of Melbourne Dermatology - Cell Structure / Oxidative Damage / The Importance of Antioxidants

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Cell Structure / Oxidative Damage / The Importance of Antioxidants

IS Clinical Skin Cell Diagram

A few additional facts should be noted about the structure of the cell as it pertains to oxidative damage and antioxidants.

They are listed here:

  1. All membranes are designed to enclose a part of the cell (as mitochondria, nucleus) or the cell itself.

Membranes are lipid-soluble (fat-soluble).

If they become damaged, they have difficulty protecting their interior structures, as well as letting the right substances in and keeping other substances out of cellular components.

Lipid-soluble antioxidants protect these and all other lipid-containing structures.

An example of a lipid-soluble antioxidant is Vitamin E, although there are also many other lipid-soluble antioxidants.

  1. The interior of cellular structures, including the interior of the cell itself, contain much water. Therefore, aqueous (water-soluble) antioxidants protect these areas. An example of an aqueous antioxidant would be Vitamin C.
  2. The DNA portion of the cell in the chromosomes of the nucleus not only directs the cell’s function but also directs the reproduction of the cell so that other similar cells can be made.

    In the case of the example above, the function of this cell is to make collagen.

    If the DNA is damaged, it may direct the formation of collagen containing "mistakes".
  3. Biochemically inaccurate collagen would be unable to function properly; it might have poor elasticity (causing wrinkles) or be unable to bind with other collagen chains (causing wrinkles, loss of resilience, improper scarring).
  4. If the mitochondria is damaged, the cell is unable to produce energy as it should. Energy is required for the cell and all of its parts to function. Also, the mitochondria, in producing energy, creates radicals as an energy source. Nature designed us to make extra energy and this unused energy begins cellular damage inside the cell’s boundaries.
  5. Once any free radical (such as solar rays, oxygen free radicals, radicals from smoking, etc.) touches the cell, the cascade of free radical damage begins, as illustrated in the above reactions.

Primary antioxidants can quench free radicals before they touch the cell or inside the cell.

It is important to have antioxidant protection at all cellular layers because it is impossible to stop all free radicals at the surface.

Many of them get through the initial skin barrier or come from inside the cell itself via cellular metabolism.

Related Skin Care Information, Products and Expert Discussions

The Free Radical Cascade / The Importance of Antioxidants

Dr. Albert Laporte

Definition of Oxidative Stress

Extent of Protection from Heliocare

Sources of Free Radical Damage


IS Clinical : IS Clinical Topics : Oxidative Stress and Free Radical Damage :

Theories of Aging : The "Free Radical" Theory of Aging : "Neurohumoral" Theory of Aging : The Cause of Disease : Inflammation : Sources of Free Radical Damage : The Skin and Free Radical Damage : Definition of Oxidative Stress : Antioxidants Can Be Harmful : The Free Radical Cascade / The Importance of Antioxidants : Cell Structure / Oxidative Damage / The Importance of Antioxidants : The Importance of The RIght Antioxidants (Highly Individualized Medically Managed Protocols) : The Lifespan Curve : Lifespan Curve A — Neanderthal Wo(Man) : Lifespan Curve B — Sewers and Household Plumbing : Lifespan Curve C — Contemporary Wo(Man) : Lifespan Curve D — Virtually Utopic? : Hindsight and Empowered Knowledge: From Curve C to D : Oxidative Stress and Free Radical Damage — Reference List : Oxidative Stress/Damage Theory of Aging Disproven by Study :


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