Skinceuticals Pigment Regulator is promoted as a "safe alternative" to 4% hydroquinone for the treatment of hyperpigmentation.
Hydroquinone is an aromatic organic compound which is a type of phenol with a variety of uses principally associated with its action as a reducing agent.
In human medicine, hydroquinone is used as a topical application in hyperpigmentation treatment and works by inhibiting an enzyme (tyrosinase) that stimulates the production of melanin. Hydroquinone is also used in photographic developing solutions and occurs naturally in some beetles and plants.
Despite inadequate evidence of carcinogenicity in humans and a record of safety and superiority in the treatment of hyperpigmentation approaching 50 years, products containing hydroquinone are increasingly sequestered as unsafe, creating a market for alternatives.
Skinceuticals Pigment Regulator contains a combination of exfoliants (Hydroxyethylpiperazine Ethane Sulfonic Acid + Glycolic Acid) and tyrosinase-inhibitors (Kojic Acid + Phyllanthus Emblica Fruit Extract).
Unlike hydroquinone, the ingredients in Skinceuticals Pigment Regulator may be used on a permanent basis if desired.
Vivité Vibrance Therapy and Biomedic Pigment Control are similar products claiming clinical equivalence to hydroquinone.
Products containing unoxidized Vitamin C such as Biomedic Potent-C, La Roche-Posay Active-C and Redermic and Obagi Professional-C can also help reduce hyperpigmentation without hydroquinone.
Elta MD UV Clear SPF 46 and Nia 24 Sun Damage Prevention SPF 30 contain niacinamide which can help reduce and prevent hyperpigmentation better than sunscreens not containing these ingredients, and may be applied after Skinceuticals Pigment Regulator for a synergistic effect.
26/5/10 — La Roche-Posay Physiological Ultra-Fine Scrub.
Skinceuticals Pigment Regulator contains sodium metabisulfite which may cause allergic reactions in those who are sensitive to sulfites.
Please note: Skinceuticals is available for online order by customers in the United States only. This product ships from the United States. Australian patients can re-order select Skinceuticals products for delivery within Australia in accordance with their prescription by logging in.