Home

View Cart/Checkout
Contact/Customer Service

Perennial / Wisdoms

UV Exposure
Aging Skin and Mature Skin
Theories of Aging
Antioxidants
Sunscreens

Skin Care

Allergan
Alyria
Anthelios
Avene
Biomedic
Blue Lizard
Cellex-C
Citrix
Clarisonic
Colorescience
Cotz
Clinique Medical
DCL
Dermatix
Elastiderm
Elta MD
Estion
Ethocyn
Exuviance
Fake Bake
Frederic Fekkai
Glycolix
Glytone
Great Lips Rx
Heliocare
IS Clinical
Jane Iredale
Jan Marini
Kinerase
Kinerase Clear
Kinerase PhotoFacials
Kinerase Pro+
Leaf & Rusher
La Roche Posay
L-M-X
M Lab
Neoceuticals
Neocutis
Neostrata
Neova
Nia24
Nordic Naturals
Obagi
Obagi Rosaclear
OC Eight
Olos
PCA Skin
Pentaxyl
Prevage MD
Remergent
Replenix
RevaleSkin
Revitalash
Scarguard
Skinceuticals
SkinMedica
Teamine
Theraplex
Ti-Silc / Z-Silc
Topix
Tricomin
VitaMedica
Zeno MD
Browse more brands.

Facial Skin Condition Treatments

Adult Acne
Broken Capillaries
Dark Circles
Deep Wrinkles
Dry Skin
Fine Lines
Hyperpigmentation
Open Pores
Puffy Eyes
Rosacea
Sagging Skin

Body Skin Condition Treatments

Aging Hands
Breast Firming
Cellulite
Hands
Keratosis Pilaris
Lips
Scalp Acne
Stretch Marks

Skin Care Ingredients

Alpha Lipoic Acid
Arginine + Serine
Asiatic Acid
Blueberry
Caffeine
Capryloyl Salicylic Acid
Ceramides
Chlorogenic Acid
Chrysin
Coffee Berry
Hydrolyzed Hyaluronic Acid
Mexoryl
Pro-Xylane
Silymarin
Sodium Laureth Sulfate/Sulphate
Browse more ingredients.

Clinical Procedures and Topics

Four Fundamentals
Absurd Skin Care
Aging Skin
Antioxidants
Botox
Enzyme Exfoliation
Free Radical Damage
French Skin Care
Glycolic Acid
Idebenone
Irrational Fears
Klein Becker
Oxidative Stress
Paula Begoun
Perricone
Restylane
Skin Structure
Stem Cells
Healthy Skin Barrier Function
Smoking
Sun Protection
Topical Vitamin C/Firming
Choices and Needs
Strivectin
Additional clinical skincare topics.

absorption academy acid adding addition advantages aesthetic agahigian against amount amounts announced antioxidant applied ascorbic attention based baseline better care chicago chief class clinically closely collagen compared competitive competitor concentration conditions content damage data degrees dermatological dermatology determined findings fold formulations future given greater harry health healthy high highly hours hspace http hydroquinone images important individual investigator investigators keeps layers lead leader leading less level lhnv looking making measured medical meeting micro month months nasdaq noshade obagi penetration performed product products professional provide provided said serum serums skin skincare skinceuticals stability study test three topical total treatment vitamin vitro vspace

Obagi Medical Products, Inc. (Nasdaq:OMPI), a leader in topical aesthetic and therapeutic skin health systems, announced the results of an in vitro study of their Obagi Professional-C and Obagi-C Rx Serums today at the American Academy of Dermatology's Summer Academy Meeting in Chicago.

The data show that Obagi-C Rx Serum (4% hydroquinone, 10% L-ascorbic acid) provided a more than 10-fold greater absorption of vitamin C than the leading competitive product, Skinceuticals 20%.

The Obagi Professional-C Serum (20%) resulted in a more than 5-fold greater absorption of vitamin C than the leading competitive product.

In addition, both Obagi Medical Vitamin C Serums were proven to have greater stability than the leading competitor, which is important given that topical vitamin C products can be unstable thus potentially making them less efficacious.

"Vitamin C is an important antioxidant and is essential for collagen production, which keeps skin looking young and healthy. It's also very sensitive to numerous external conditions, so it is important to use a formulation that has a high level of penetration and is stable," said Harry Agahigian, lead investigator of the study. "The studies showed that the Obagi Medical vitamin C formulations provide much better absorption and greater stability versus the competitive product."

Obagi vs. Skinceuticals Key Findings — Absorption

Investigators sought to evaluate the absorption and stability of the three serums and the Obagi serums performed better in each objective of the study.

In an in vitro test evaluating absorption of vitamin C, each of the three serums (Obagi-C Rx Serum, Obagi Professional-C 20% Serum and the 20% L-ascorbic acid-based leading competitor product) was tested by being applied to cadaver skin for a period of 19 hours at 37 degrees C.

The total absorption of vitamin C in each product was:

• 148 micro-g with Obagi-C Rx Serum (31% of baseline amount);
  
  
• 66 micro-g with Obagi Professional-C Serum (11% of baseline amount);
  
  
• 12 micro-g with the competitor product (2% of baseline amount).

Total absorption was calculated by adding amounts of L-ascorbic in the reservoir, determined at .5, 1.5, 3.0, 6.0, 10.5 and 19 hours.

When compared to Skinceuticals vitamin C serum in a recent study, the vitamin C serum in the Obagi-C Rx System provided 50% more penetration into the layers of the skin to provide greater antioxidant therapy and effectiveness."

Obagi vs. Skinceuticals Key Findings — Stability

In a stability test, the serums, Obagi-C Rx Serum (4% hydroquinone, 10% L-ascorbic acid), Obagi Professional-C Serum (20% L-ascorbic acid), and leading competitor 20% L-ascorbic acid, were stored at 40 degrees C and the vitamin C content was measured at 1 and 3 months.

An additional stability test was performed by storing the products at 45 degrees C for 1 month.

Here, vitamin C content was also measured.

"We are proud that our vitamin C products provide such clinically significant advantages over the competitive product," said Steven Carlson, Chief Executive Officer of Obagi Medical Products. "Obagi Medical's top priority is to provide highly effective differentiated skin care products that are based in real science. We do that by working closely with the top experts in the skin care field."

Source: Obagi Medical Products via Wire — July 31, 2008.

NB: Patients should not change their skincare outside of individual dermatological attention.

Skinceuticals Skin-Penetration Data