Skin Care and Treatments of Melbourne Dermatology - Obagi Medical Products Presents In Vitro Data Showing Its Topical Vitamin C Serums Provide Greater Absorption and Stability Than a Leading Competitor

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Obagi Medical Products Presents In Vitro Data Showing Its Topical Vitamin C Serums Provide Greater Absorption and Stability Than a Leading Competitor

Obagi Medical Products Presents In Vitro Data Showing Its Topical Vitamin C Serums Provide Greater Absorption and Stability Than a Leading Competitor

Obagi Professional-C Serum and Obagi-C(R) Rx Serum Provide Advanced Topical Vitamin C to Prevent Premature Signs of Aging and Protect Against Future Damage

Obagi Medical Products, Inc. (Nasdaq:OMPI), a leader in topical aesthetic and therapeutic skin health systems, announced the results of an in vitro study of their Obagi Professional-C and Obagi-C Rx Serums today at the American Academy of Dermatology's Summer Academy Meeting in Chicago.

The data show that Obagi-C Rx Serum (4% hydroquinone, 10% L-ascorbic acid) provided a more than 10-fold greater absorption of vitamin C than the leading competitive product, Skinceuticals 20%.

The Obagi Professional-C Serum (20%) resulted in a more than 5-fold greater absorption of vitamin C than the leading competitive product.

In addition, both Obagi Medical Vitamin C Serums were proven to have greater stability than the leading competitor, which is important given that topical vitamin C products can be unstable thus potentially making them less efficacious.

"Vitamin C is an important antioxidant and is essential for collagen production, which keeps skin looking young and healthy. It's also very sensitive to numerous external conditions, so it is important to use a formulation that has a high level of penetration and is stable," said Harry Agahigian, lead investigator of the study. "The studies showed that the Obagi Medical vitamin C formulations provide much better absorption and greater stability versus the competitive product."

Obagi vs. Skinceuticals Key Findings — Absorption

Investigators sought to evaluate the absorption and stability of the three serums and the Obagi serums performed better in each objective of the study.

In an in vitro test evaluating absorption of vitamin C, each of the three serums (Obagi-C Rx Serum, Obagi Professional-C 20% Serum and the 20% L-ascorbic acid-based leading competitor product) was tested by being applied to cadaver skin for a period of 19 hours at 37 degrees C.

Obagi vs. Skinceuticals Skin Penetration.

The total absorption of vitamin C in each product was:

Total absorption was calculated by adding amounts of L-ascorbic in the reservoir, determined at .5, 1.5, 3.0, 6.0, 10.5 and 19 hours.

When compared to Skinceuticals vitamin C serum in a recent study, the vitamin C serum in the Obagi-C Rx System provided 50% more penetration into the layers of the skin to provide greater antioxidant therapy and effectiveness."

Obagi vs. Skinceuticals Key Findings — Stability

In a stability test, the serums, Obagi-C Rx Serum (4% hydroquinone, 10% L-ascorbic acid), Obagi Professional-C Serum (20% L-ascorbic acid), and leading competitor 20% L-ascorbic acid, were stored at 40 degrees C and the vitamin C content was measured at 1 and 3 months.

An additional stability test was performed by storing the products at 45 degrees C for 1 month.

Here, vitamin C content was also measured.

Obagi vs Skinceuticals In Vitro Data.

"We are proud that our vitamin C products provide such clinically significant advantages over the competitive product," said Steven Carlson, Chief Executive Officer of Obagi Medical Products. "Obagi Medical's top priority is to provide highly effective differentiated skin care products that are based in real science. We do that by working closely with the top experts in the skin care field."


Source: Obagi Medical Products via Wire — July 31, 2008.

NB: Patients should not change their skincare outside of individual dermatological attention.

Obagi Professional C Serums

Skinceuticals Skin-Penetration Data

Vitamin C Serum - Absorption by Percentage Concentration

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Obagi :

Obagi Nu-Derm : Obagi-C Rx : Obagi Professional-C : Obagi Clenziderm : Obagi Rosaclear : Elastiderm : Obagi Archive : Obagi Medical Products Presents In Vitro Data Showing Its Topical Vitamin C Serums Provide Greater Absorption and Stability Than a Leading Competitor :


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