Skin Care and Treatments of Melbourne Dermatology - Priori

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Priori

Priori

Sunday, 22 June 2008

Foregone Conclusions: Priori and Prevage with Idebenone

Wealthy skincare manufacturers must truly take pause to snigger at the infinitely monetizable paradox many aging women choose to represent.

Namely, to voice real concern over their changing appearance, while simultaneously being compelled to repeatedly shoot themselves in the foot over an extended, critical period of time, ensuring lasting, permanent damage and perpetual dissatisfaction.

Dissatisfaction which typically results in increasing amounts of unrealistic treatment, coupled with bouts of apathy which do nothing to increase the likelihood of the right decisions ever being made for any meaningful period of time.

Use of Idebenone (a topical antioxidant ingredient found in Prevage and Priori) is ideally representative of the ease with which individuals will "anti-aging treatment" to degenerate into farce.

In every instance, combination 15% ascorbic acid and 1% tocopherol treatment is markedly more effective at preventing permanent skin damage than any available idebenone formula — either Prevage (from Allergan) or the less impressive Priori copycat formula which has been piggybacking on Prevage's popularity.

Priori does at least contains idebenone, something the parasites at Basic Research saw fit to leave out of their "Sovage with Idebenol."

Research and testing for topical idebenone has only ever been an in-house, biased affair because individual's conducting clinical trials stood to gain financially from reporting positive results for topical idebenone.

In contrast, objective third-party (peer-reviewed) testing was conducted at Duke University for combination ascorbic acid and tocopherol.

Neither is combining ascorbic acid and tocopherol proprietary, although its rarely done to skin's benefit.

Prevage and Priori's comparisons between idebenone and combination ascorbic acid and tocopherol are made using concentrations of C & E at a fraction of those used in practice.

The fiction of its superiority continues with the form of idebenone available through the department stores and beauticians being weaker than the studied amounts.

In contrast, the formula studied at Duke University is identical to the original "C & E" product.

Experience also bears out the plain facts because even longer-term users of idebenone present with skin statistically similar to the mean for their age.

The situation is rarely remedied because individuals are adamant that their antioxidant choice represents sound judgement, undistorted by wishful thinking or marketing.

Idebenone marketing alludes to higher levels of prevention to satisfy consumers drawn to science, but whom for whatever reason lack the inclination or ability to apply the realism their skincare approach would seem to mandate.

Certain skincare manufacturers toy with the women who make up this quasi-scientific skincare-using community like cats with mice, only allowing them so much freedom before they knock them back in the direction of their latest survivalist ingredient for another round of idiocy.

Masochistically, these women tend to serially return to the same chintzy stores that instigated unnecessary permanent aging of their skin in the first place.

Dogged brand and ingredient evangelism is a practice fostered and enjoyed by beauty therapists and the cosmetics industry.

Although possibly well-meaning, this is quintessentially a rehearsed marketing behaviour individuals internalise to their detriment.

You may choose to implement idebenone as an auxiliary antioxidant, however its use alone, or in place of individually superior alternatives, is technically negligent.

Using idebenone in place of the independently-reviewed ascorbic acid and tocopherol acetate formula, and genuinely expecting to limit aging to the same (or better) degree, is like yelling at the sun in a bid to stop it setting at the end of the day.

Tuesday, 13 October 2009

Idebenone — Prevage and Priori vs Skinceuticals C E Ferulic

Idebenone — Prevage and Priori vs Skinceuticals C E Ferulic

Idebenone is closely related to co-enzyme CoQ-10 (ubiquinone) and is turning up in a variety of skin care products such as Priori and Prevage in various concentrations, both inconsequential and useful.

Understanding the Benefits of Antioxidants for Skin

The ability of an antioxidant to reduce the aging impact of the sun on skin can be scientifically measured by its ability to reduce the formation of sunburn cells.

Skin registers lasting sun damage on a daily basis, irrespective of the season and whether or not it appears outwardly burnt.

Indeed, its the invisible damage, produced primarily by UVA rays which penetrate the dermis, that do the most (and potentially lethal) damage.

No matter how high the SPF, sunscreens can unfortunately only block about half the damage the sun exacts.

Antioxidants are the other side of the equation.

Priori and Prevage (Idebenone), C E Ferulic and Protection

One per cent idebenone outperforms the same percentage of ascorbic acid (vitamin C) and vitamin E (tocopherol) at around $220.00 per 30 mL (1 oz.) in tests that measure the reduction in formation of sunburn cells when human skin is placed under the oxidative stress of sun exposure.

Its been this comparison which has led many to believe that idebenone is now the antioxidant of choice.

While on the surface it may appear that idebenone is more effective than the traditionally used (and well-studied) antioxidants, its important to keep in mind that:

  • in clinical settings vitamin C and E are not used at one percent;
  • higher percentages of idebenone do not appear to increase its antioxidant potential.

Skinceuticals C E Ferulic for example utilizes a synergistic stabilized combination of vitamins C, E and ferulic acid (a botanical antioxidant) at 15%, 1% and 0.5% respectively.

Both vitamin C and vitamin E at these percentages individually reduce the formation of sunburn cells more effectively than idebenone alone.

Moreover vitamin C, E and ferulic acid formulated together are almost three times more effective than Idebenone alone at reducing sunburn cell formation:

Idebenone — Prevage and Priori vs Skinceuticals C E Ferulic - Comparing Idebenone, C, Ferulic, E and Ubiquinone.

Skinceuticals' C E Ferulic serum formula provides no less than eight times the skin's natural photoprotection:

Idebenone — Prevage and Priori vs Skinceuticals C E Ferulic - Erythema Prevention and Sunburn Cell Reduction.

The only means to achieving near-perfect sun protection and defense against skin cancer and signs of skin deterioration including textural changes, irregularity in colouring and the collagen degradation that leads to wrinkling is to make daily use of both a proven, potent, stable antioxidant and a true broad spectrum sunscreen — two things which are few and far between.

Further Information

Wednesday, 7 February 2007

Priori Skin Care References

Related Skin Care Information, Products and Expert Discussions

La Mer

Ti-Tan

Yu-Be

Sea & Ski

Lux


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New/Notable 2016

Open Pores — Treatment and Prevention

MD Rx Melbourne Dermatology Open Pores Overnight Solution

The Sun

Radiation

Mexoryl

Pentapeptides Ineffective

Asiaticoside vs. Madecassoside for Collagen Synthesis

La Roche-Posay Redermic

Valeant Pharmaceuticals

Rainbow

Telomerase

Azelaic Acid

Bisabolol

Avena Sativa

Panthenol

Aster Family of Plants

Green Tea (Camellia Sinensis) Extract

Polyphenols

Caffeine

Oxofulleram

Salicylic Acid

Capryloyl Salicylic Acid

Open Pores

Phytosphingosine

Glycerin

Idebenone

Ascorbyl Palmitate

Kojic Acid

Algorithm for Optimal Sustained Exfoliation: Glycolic Acid

Comparison of 33 Sunscreens