Silymarin provides statistically significant improvement to rosacea.
In particular, improvement of skin redness, papules, itching, hydration, and skin color are observed in rosacea patients using skin care containing Silymarin.
Flavonolignans from Silybum Marianum also Moderate UVA-Induced Oxidative Damage to HaCaT Keratinocytes.
For further information, see the Silymarin Monograph, Milk Thistle and About Milk Thistle Preparation.
Rosacea patients can also refer to the comprehensive list for silymarin/silybum.
Silymarin for facial use is available to rosacea patients in Skinceuticals Face Cream.
"The action can be considered multicentric and multiphase because of the direct modulating action on cytokines and angiokines normally involved and up-regulated in the case of such skin condition."
Combined effects of silymarin and methylsulfonylmethane in the management of rosacea: clinical and instrumental evaluation.
Berardesca E, Cameli N, Cavallotti C, Levy JL, Piérard GE, de Paoli Ambrosi G.
San Gallicano Dermatological Institute, Rome, Italy.