Skin Care and Treatments of Melbourne Dermatology - Selenium

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Selenium

Selenium

Selenium Toner

For all the available information, careful intake of a few fresh brazil nuts a day and some topical skin care containing selenomethionine should serve as perfect prophylaxis against a plethora of partially avoidable woes encompassing poor skin quality, cancer, arthritis and poor immunity.

Jan Marini C-ESTAMINS provides 500 micrograms of selenium per day (along with a diversity of other beneficial though often hard to acquire nutrients), a dose recognised as providing therapeutic rather than maintenance benefit, although if you take Jan Marini C-ESTAMINS you should not also eat generous amounts of brazil nuts on a regular basis.

Kodak Selenium Toner is an artistic photographic tool and is not for cutaneous application(!).

Saturday, 29 December 2007

Bad Cholesterol and Oxidative Stress

Some population surveys have suggested an association between lower antioxidant intake and a greater incidence of heart disease.

Evidence also suggests that oxidative stress from free radicals, which are natural by-products of oxygen metabolism, may promote heart disease.

For example, it is the oxidized form of low-density lipoproteins (LDL, often called "bad" cholesterol) that promotes plaque build-up in coronary arteries.

Selenium is one of a group of antioxidants that may help limit the oxidation of LDL cholesterol and thereby help to prevent coronary artery disease.

Currently there is insufficient evidence available to recommend selenium supplements for the prevention of coronary heart disease; however, the SU.VI.MAX study is looking at the effects of antioxidant nutrients such as selenium on heart disease.

Monday, 22 June 2009

Effect of Topical Selenium on Skin

Regular selenium penetrates poorly and should not be expected to yield beneficial antioxidant and anti-inflammatory properties owing to resultant poor or non-existent bioavailability however selenium as selenomethionine form penetrates the skin and should therefore be bioavailable.

Thursday, 27 December 2007

Effectiveness of Selenium Against Skin Cancer and Basal Cell Carcinoma

Selenium supplementation is ineffective at preventing skin cancer and basal cell carcinoma.

Dermatologist, Dr Cheryl M Burgess, Cosmetic Dermatology, Springer-Verlag Publishers.

Sunday, 9 August 2009

Health Risks of Excess Selenium

High blood levels of selenium can result in a condition called selenosis.

Symptoms of selenosis include gastrointestinal upsets, hair loss, white blotchy nails, garlic breath odor, fatigue, irritability, and mild nerve damage.

Selenium toxicity is rare.

The few reported cases have been associated with industrial accidents and a manufacturing error that led to an excessively high dose of selenium in a supplement.

The Institute of Medicine of the National Academy of Sciences has set a tolerable upper intake level (UL) for selenium at 400 micrograms per day for adults to prevent the risk of developing selenosis.

Review the List of Foods High in Selenium, Recommended Daily Allowance of Selenium, Recommended Dietary Allowances (RDA) for Selenium for Children and Adults (Pregnant or Lactating or Not) and Selenium Intake Upper Limits.

Friday, 28 December 2007

Incidence of Non-Melanoma Skin Cancer in the US as Pertaining to Selenium

The incidence of non-melanoma skin cancer is significantly higher in areas of the United States with low soil selenium content.


Studies examining the relationship between dietary selenium intake and risk of various cancers have shown that low selenium intake is associated with higher cancer rates.

A recent well-controlled intervention trial studied whether selenium supplementation can prevent cancer in subjects who have a history of skin cancer and live in areas of the United States with low soil selenium levels.

Selenium supplementation did not reduce skin cancer rates, but the incidence of total, lung, colorectal, and prostate cancers was significantly reduced by the intervention.

Although these data need confirmation, they suggest that adequate selenium intake is essential for cancer prevention.


Fleet JC. Dietary selenium repletion may reduce cancer incidence in people at high risk who live in areas with low soil selenium. Nutr Rev 1997;55:277-9.

Jean Mayer USDA Human Nutrition Research Center, Tufts University, Boston, MA 02111, USA.

Saturday, 29 December 2007

List of Foods High in Selenium

Brazil nuts — very high and irregular selenium content, eat only occasionally, with just 30 grams providing up to 8 times the US FDA RDA.

Tuna — 100 grams contains approximately 95% the current US FDA RDA.

Cod — 100 grams contains approximately 45% the current US FDA RDA.

Also refer the RDA (US FDA Recommended Daily Allowance) for Selenium and Selenium Intake Upper Limits.

Thursday, 3 January 2008

Recommended Daily Allowance of Selenium

The recommended daily allowance for selenium is the same for men as for women, at 55 micrograms/day.

Habitual intake of 200 micrograms/day has been shown to prevent lung, colorectal and prostate cancers.

From selenosis: current evidence suggests that a daily selenium consumption for [(wo)]man of approximately 30 micrograms is necessary to prevent the selenium-deficient syndrome, Keshan disease, while approximately 90 micrograms/day/adult should be the minimum daily requirement for optimum biological performance.

Refer the upper safe limit for selenium.

Saturday, 29 December 2007

Recommended Dietary Allowances (RDA) for Selenium for Children and Adults (Pregnant or Lactating or Not)

Irrespective of gender:

  • 1 to 3 years: 20 micrograms.
  • 4-8 years: 30 micrograms.
  • 9-13 years: 40 micrograms.
  • 14-18 years and above: 55 micrograms (60 micrograms during pregnancy, 70 micrograms while lactating).

See the additional notes on Recommended Daily Allowance of Selenium.

Friday, 5 June 2009

Selenium Inhibits Skin-Damaging UV-Induced Inflammatory Cytokines

Refer Photoprotection of UV-Irradiated Human Skin: An Antioxidative Combination of Vitamins E and C, Carotenoids, Selenium and Proanthocyanidins.

Thursday, 3 January 2008

Selenium Intake Upper Limits

The upper limit for daily adult selenium intake is 400 micrograms per day over 14 years irrespective of gender.

Otherwise:

  • From zero to 6 months — 45 micrograms;
  • From 7 to 12 months — 60 micrograms;
  • From 1 to 3 years — 90 micrograms;
  • From 4 to 8 years — 150 micrograms
  • From 9-13 years — 280 micrograms.

Within selenosis, a maximum range of 1000 to 1500 micrograms/day is postulated.

Friday, 28 December 2007

Selenium References

Selenium References

Saturday, 29 December 2007

Selenium and Arthritis

Surveys indicate that individuals with rheumatoid arthritis, a chronic disease that causes pain, stiffness, swelling, and loss of function in joints, have reduced selenium levels in their blood.

In addition, some individuals with arthritis have a low selenium intake.

The body's immune system naturally makes free radicals that can help destroy invading organisms and damaged tissue, but that can also harm healthy tissue.

Selenium, as an antioxidant, may help to relieve symptoms of arthritis by controlling levels of free radicals.

Current findings are considered preliminary, and further research is needed before selenium supplements can be recommended for individuals with arthritis.

Saturday, 29 December 2007

Selenium and HIV

HIV/AIDS malabsorption can deplete levels of many nutrients, including selenium.

Selenium deficiency is associated with decreased immune cell counts, increased disease progression, and high risk of death in the HIV/AIDS population.

HIV/AIDS gradually destroys the immune system, and oxidative stress may contribute to further damage of immune cells.

Antioxidant nutrients such as selenium help protect cells from oxidative stress, thus potentially slowing progression of the disease.

Selenium also may be needed for the replication of the HIV virus, which could further deplete levels of selenium.

An examination of 125 HIV-positive men and women linked selenium deficiency with a higher rate of death from HIV.

In a small study of 24 children with HIV who were observed for five years, those with low selenium levels died at a younger age, which may indicate faster disease progression.

Results of research studies have led experts to suggest that selenium status may be a significant predictor of survival for those infected with HIV.

Researchers continue to investigate the relationship between selenium and HIV/AIDS, including the effect of selenium levels on disease progression and mortality.

There is insufficient evidence to routinely recommend selenium supplements for individuals with HIV/AIDS, but physicians may prescribe such supplements as part of an overall treatment plan.

It is also important for HIV-positive individuals to consume recommended amounts of selenium in their diet.

Monday, 22 June 2009

Source of Selenium's Ability as an Antioxidant and Anti-Inflammatory — Dr. Jeannette Graf

"Selenium’s protective ability lies in its essential role as a cofactor in the formation of the important protective enzyme glutathione peroxidase."

Dr. Jeannette Graf.

Saturday, 29 December 2007

Symptoms of Selenium Deficiency

From selenosis:

The signs and symptoms of selenium deficiency closely simulate each other for animals and man.

Severe deficiency is characterized by cardiomyopathy while moderate deficiency results in less severe, myodegenerative syndromes such as muscular weakness and pain as well as a variety of other selenium-associated diseases.

Clinical manifestations of many of these disorders require contributory factors, such as stress, to precipitate symptoms which are documented for animals and implicated for humans.

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