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Skinceuticals is a Franco-American company that develops dermatology products based primarily on high concentration, high-purity antioxidant technologies intended to help prevent, manage and partially reverse visible photoaging.

To achieve the results described, patients generally require highly personalised ongoing care and education.

Skinceuticals Clinical Experiences

Use of Skinceuticals antioxidant skincare products may be contraindicated in patients with sensitive skin, inflammatory disorders (including rosacea) or acne.

The use of other Skinceuticals products is also generally contraindicated outside of professional attention if employed concurrent with other therapies including ablative and non-ablative laser resurfacing, chemicals peels, retinoids and alpha hydroxy acids, among others.

Undesirable and subclinical inflammatory side effects of topical antioxidant use are an ongoing concern, even among healthy individuals, although data provided by Skinceuticals indicates their most popular product (Skinceuticals C E Ferulic) is well tolerated, efficacious and highly effective against photoaging.

Poor, counterproductive and possibly even harmful outcomes are nevertheless sometimes recorded where users are in poor health, receive little exposure to UV (a symptom of of both changing behavioural and topical photoprotection), are taking medications, have used topical steroids, or spend considerable amounts of time exposed to computer screen radiation.

Such clinical observations lend impetus to the biological anti-aging potential of topically applied antioxidants, but also to the notion that excessive or contraindicated use is pro-oxidant, or in other words a cause of oxidative stress, free radical damage and therefore premature aging.

Skinceuticals skin care use outside of measured, professional attention may be a cause of disease far greater than the typical skin care failure paradigm predicated on alternating states of imagined benefit and disappointment, and which results in actual, active harm by treatment rather than passive harm by neglect.

Skinceuticals Experiences and Feedback

Feedback in prior years from many pre-existing users of Skinceuticals skin care products and treatments indicated that they had, in the main, extracted little or nothing of the positive potential latent within the ingredients offered by the brand.

For this to be the case, use must be inappropriate or incorrect to some degree.

Use of counterfeit, home-made, expired or oxidized ascorbic acid serums is entirely inappropriate and appears largely attributable to beauty therapy and the skincare practices it has disingenuously fostered over the years in purporting care.

Use of samples, such as Skinceuticals C E Ferulic samples, is also problematic.

Skinceuticals C E Ferulic Reviews are available.

Skinceuticals Highlights

Providing their use is fitting, a number of Skinceuticals products stand tall above the crowded skin care marketplace.

Skinceuticals Foaming Cleanser is arguably one of the best facial cleansers available and Skinceuticals Clarifying Clay Mask one of the most effective and quick (albeit temporary) fixes for visibly open pores and dull, stressed skin since the disappearance of La Prairie's Cellular Purifying Clay Mask in the late 1990s.

Skinceuticals Serum 20 AOX+ builds great firmness in skin over periods of use in excess of four months, however may stimulate acne and will harden the epidermis in the absence of ideal moisturisation.

Skinceuticals C E Ferulic is publicly Skinceuticals' main claim to fame, their most popular product by a huge margin, the successor to Skinceuticals C + E (which appears to have reappeared as IS Clinical C & E) and is supported by Duke University research published in peer-reviewed dermatological journals.

Skinceuticals C E Ferulic appears to be well tolerated (particularly in patients with normal to dry skin), but may provide less absorbable and firming Vitamin C than the Vitamin C Serums formulated without Vitamin E (Eye Gel AOX+, Serum 10 AOX+, Serum 15 AOX+ and Serum 20 AOX+).

A small number of individuals have cleverly combined the use of Skinceuticals C E Ferulic with Skinceuticals Serum 20 AOX+ or lesser strengths (Serums 10 AOX+ and 15 AOX+) to produce greatly enhanced results.

Skinceuticals C E Ferulic Reviews are available.

Skinceuticals Eye Gel AOX+ and Antioxidant Lip Repair are great ways in which to firm, condition and generally improve the defense of the periocular and lip regions against photoaging as sunscreen use is contraindicated or wears away too rapidly to be of much use.

The Skinceuticals Sunscreens — in particular Daily Sun Defense SPF 20 and Ultimate UV Defense SPF 30 — are superior sunscreens for daily, permanent use, providing a high level of protection against aging UVA, the trojan horse of premature aging of the skin if used as directed, chemical encapsulation to avoid allergic reactions and possible negative side effects from long-term use (see Review of Hamilton Sunscreens), and wear elegantly on the skin.

Skinceuticals' use of sodium hyaluronate, silymarin/silybum, centella asiatica, petrolatum and soy isoflavones is especially pure and innovative.

Skinceuticals Advanced Body Firming Lotion is one of only a handful of body lotions and creams which provide a level of treatment normally only dispensed for facial use.

Skinceuticals Compare and Contrast

Most manufacturers of cosmeceutically-marketed skin care products appear well attuned to the insurmountable difficulty of providing anything more than the idea of results (see Klein-Becker, Strivectin, Amatokin and Decleor, among many others), and to the legal dilemma of attempting to satisfy uneducated, unrealistic consumers experiencing aging crises.

Accordingly most topical antioxidant skincare is not absorbed into the dermis, the genesis of wrinkling changes, and most skincare products packaged or marketed in a manner similar to this brand are charlatan in nature.

Historically, Skinceuticals formulations have owed much to the work of Drs. Sheldon Pinnell and Omar Mustafa and are evolutionarily related to Cellex-C and IS Clinical.

Although renown for its Vitamin C (as ascorbic acid) serums, topical Vitamin C (like many ingredients) has been available and used to good effect outside of beauty therapy and the department stores since the 1950s.

Like worthwhile photoprotection, the public at large typically requires several decades (or longer) to come around to meaningfully effective ways of treating and protecting the skin.

Jan Marini Skin Research provides related skin care and appears to be associated with fewer negative side effects, however meaningful comparisons between the two companies' approaches (for example ascorbic acid vs. ascorbyl palmitate) are unavailable and unlikely to be forthcoming.

Skinceuticals Retinol is compared with that of Jan Marini (Factor A) and Gernetic (Nuclea) in the clinical monograph Retinoid vs. Retinoid — Jan Marini, Skinceuticals, Gernetic 6 Month Programs and Visia Analysis.

Skinceuticals Further Information

Review the clinical documents collected under Skinceuticals Reviews, Monographs, Clinical Studies and Results in addition to A Year of Photoprotection, Retinoid vs. Retinoid — Jan Marini, Skinceuticals, Gernetic 6 Month Programs and Visia Analysis and the Silymarin Monograph.

Peruse Skinceuticals C E Ferulic Reviews.

Skinceuticals is discussed in the Cosmetic Dermatology Newsletter of Summer 2007.

Aspects of the Gernetic France Age Management Guide pertain to advanced Skinceuticals usage.

A Selection of Skinceuticals Updates

Review the Silymarin Monograph and Silymarin skincare reference list for advanced anti-aging and preventative usage information.

New — Skinceuticals Epidermal Repair is specifically formulated for skin compromised by cosmetic procedures ranging from microdermabrasion to laser resurfacing, as well as skin sensitized by retinoid therapy or environmental aggressors.

31/3/08 — Skinceuticals Intense Line Defense.

20/1/08 — Skinceuticals Foaming Cleanser/SPF 20/B5 Gel Special Set.

12/1/08 — Effects of Oxidised and Denatured Ascorbic Acid.

21/12/07 — Skinceuticals C E Ferulic Samples Discussion.

19/12/07 — Photoaging — Update and Treatment, Sheldon R. Pinnell.

3/12/07 — Skinceuticals Antioxidant Storage Notes.

28/11/07 — New Clinical Study: Skinceuticals C E Ferulic — Dermatological Evaluation of Tolerance and Efficacy.

28/11/07 — New Clinical Study: Skinceuticals C E Ferulic — Evaluation of Effects on Special Molecular Biomarkers of Oxidative Stress in Skin of Healthy Subjects After UVA 1 Irradiation.

16/11/07 — New Skinceuticals Active UV Defense with Mexoryl SX.

21/10/07 — Skinceuticals Light and Easy Extended Skin Resurfacing/Freshening.

21/10/07 — Skinceuticals Normal to Dry Skin Reconditioning Massage.

18/10/07 — New Skinceuticals Micro-Polish Procedure.

18/10/07 — New Skinceuticals Hydrating B5 Mask.

30/07/07 — Foregone Conclusions: Priori and Prevage with Idebenone.

29/03/06 — Idebenone: Prevage and Priori vs Skinceuticals C E Ferulic.

25/03/06 — Skinceuticals Vitamin C Serums — General Advice.

Skinceuticals Products Overview

• An Introduction to Skinceuticals
• Skinceuticals Patient Login Products and Topics
• Skinceuticals Reviews, Monographs, Clinical Studies and Results
• Skinceuticals Aficionado Topics
• Skinceuticals Procedures
• 102 Skinceuticals Clinical Procedures and Topics
• Skinceuticals Treatment Nodes Updated in the Last Week — 2 Sections
• Skinceuticals Serums - Topical Antioxidants
• Skinceuticals Facial Cleansers and Masks
• Skinceuticals Toners
• Skinceuticals True Broad Spectrum Moisturizing Sunscreens
• Skinceuticals Corrective Moisturizing Treatments
• Skinceuticals Skin Maintenance/Tone Balancing Moisturizers
• Skinceuticals Evening Skin Resurfacing Treatments
• Skinceuticals Retinol
• Skinceuticals Hyperpigmentation Treatments
• Skinceuticals Eye Contour Treatments
• Skinceuticals Body Treatments
• Skinceuticals Skin Systems
• Skinceuticals Acne Treatments
• Skinceuticals Skin Care References for All Products and Treatments — 46 Sections
• Skinceuticals Downloads
• Skinceuticals C E Ferulic Introductory Offer — Expired
• Skin Care References for Skinceuticals

Skin Care References for Skinceuticals

• Comparison of 33 Sunscreens
• Gernetic
• Jan Marini C-ESTA Lipid Soluble Vitamin C with DAE Complex
• Enhancing Absorption and Penetration of Topical Vitamin C
• 1000x Epidermal Hydration = Maximally Plump/Moist Skin
• Peptides in Skin Care
• Skinceuticals C E Ferulic Study - Methods
• A Topical Antioxidant Solution Containing Vitamin C, Vitamin E, and Ferulic Acid Prevents Ultraviolet Radiation-Induced Caspase-3 Induction in Skin
• Photoprotected Smoker's Skin
• On The Winter Solstice - Think Summer Sun Protection
• Skinceuticals C E Ferulic Review #5
• Unsafe Flattery: Counterfeit Jan Marini Age Intervention Eyelash
• More About Skinceuticals
• Skinceuticals Broken Capillary Protocols
• Introducing New Skinceuticals AOX+ Antioxidants
• About Skinceuticals SM — Salicylic and Mandelic Acid Peel
• Facial Spider Veins — Information and Solutions
• An Introduction to Skinceuticals Topical Antioxidant Therapy