Skinceuticals Retinol contains a form of Vitamin A used in the treatment of acne, photoaging (cumulative sun damage) and visibly open pores.
It's also the prime means by which individuals with already good skin can create dramatically better skin is every major regard.
Either Skinceuticals Retinol strength works by causing the outer layer of the skin to grow more rapidly, as it did in younger years, producing the natural consequence of a reduction in the amount of keratin protein in the skin.
Subsequently the skin's surface layer of dead skin cells reduces at a rate in line with its increased renewal, greatly reducing the likelihood of acne, a variety of lesions, and pores being stretched by retained, plugging debris.
Because retinol ties exfoliation directly to renewal, it should not be possible to over-exfoliate or damage the skin with this agent in a medical setting.
The 0.5% strength of Skinceuticals Retinol should be used by individuals who have never used a topical therapeutic retinoid such as retinoic acid. Retinyl palmitate is not a therapeutic retinoid and doesn't produce biological activity in the skin (J. Am. Acad. Dermatol. 39:S2-7,1998), yet most skin care products which list retinol as an ingredient actually contain retinyl palmitate.
The 1% strength is reserved for prior users of therapeutic retinoids, and those acclimatized to Skinceuticals Retinol 0.5% without issue.
Like topical Vitamin C, retinol suffers from inherent instability and rapidly degrades into a useless molecule when exposed to light.
Many skin care products containing retinol are unlikely to be formulated or packaged in the absence of light and air.
Because retinol is rapidly degraded by light, it makes sense to only apply Skinceuticals Retinol in the evening.
La Prairie Stimulus Complex AM is an all-in-one alternative for those in need of twice daily retinol, with sunscreens and antioxidants added to improve stability.
It's also possible, and likely better, to apply Skinceuticals Retinol immediately under Skinceuticals Face Cream and SPF 20 or 30 in case of morning use, waiting between each layer.
Packaging of Skinceuticals Retinol is ideal given the active ingredient's instability – the aluminium package shuts out all light and the pump extracts the light-weight cream without introducing air into the container.
This type of pump is characteristically slow to operate, but also helps prevent potentially irritating and wasteful over-application.
Skinceuticals Retinol exhibits the same or better effectiveness as prescription alcoholic and cream-based retinol in most instances, without the side effects often associated with these dermatological agents.
Moreover, this form of stabilized retinol penetrates skin better (J. Invest. Dermatol. 109:301-05, 1997).
Skinceuticals have enhanced this treatment's benefits beyond those of retinol alone by including:
- the potent photoprotective antioxidant silymarin to reduce photosensitivity (a side effect of retinol use) which favours new and increased daytime damage if sunscreen and antioxidants are inadequate;
- a soothing yeast-derived anti-inflammatory molecule, phytosphingosine, which aids in restoring a compromised, dry-prone and fragile skin barrier – a symptom of aging or dry skin normally exacerbated by retinol use – and is also seen to induce cancer cell apoptosis (by direct activation of caspase 8 and by mitochondrial translocation of Bax and subsequent release of cytochrome c into cytoplasm);
- molecules extracted from passiflora, hypericum perforatum, chamomile and matricaria which reduce and help prevent erythema and irritation – typically short-term side effects of early stages of retinol use usually referred to as retinoid dermatitis;
- penetration-enhancing laureth;
- a base of butyrospermum parkii, ceramides, triglycerides and cholesterol combined with silky silicones to provide controlled, comforting non-comedogenic lipids for any skin type, from very dry to very oily, ensuring even, steady and thorough delivery of retinol through the stratum corneum.
Skinceuticals Retinol is an effective alternative to prescription retinoids with some superior therapeutic and cosmetic effects, the highest concentration of retinol found in any similar product and ideal formulation characteristics.
Patients with sensitive skin and those wishing to avoid the heavy, sudden peeling of prescription alternatives will greatly appreciate and value its use where appropriate:
The Skinceuticals Retinoids
Retinoid vs. Retinoid