Skinceuticals Serum 20 AOX+: Melbourne Dermatology Skin Care

absorption acid acne addition additional against aging anti antioxidant antioxidants apply ascorbic ascorbyl available bioclear body care class clinical code collagen combination compared concentration containing cream daily damage deeper defense delivery effective effects enhanced esta evening face facial ferulic fine firming free greater healthy http images information ingredients levels lhnv light lines lotion magazine marini normal noshade obagi oily once open order palmitate particularly patients penetrating penetration phloretin photoaging photoprotection pores prevent primary product production products professional protection provide results retinol sensitive serum serums size skin skincare skinceuticals stable states sunscreen sunscreens topical treatment united used using vitamin vspace within

Home

Perennial / Wisdoms

Skin Care

Facial Skin Condition Treatments

Body Skin Condition Treatments

Skin Care Ingredients

Clinical Procedures and Topics

Skinceuticals Serum 20 AOX+

Instructions for Use of Serum 20 AOX+ by Skinceuticals

Enhancing Absorption and Penetration of Topical Vitamin C

Ingredients for Skinceuticals Serum 20 AOX+

Skinceuticals Serum 20 AOX+ Supply Notes

Skinceuticals Antioxidant Storage Notes — Protective/Preservative Refrigeration

Skinceuticals Serum 20 — Media

Antioxidant Outline Refined to Focus on Primary Antioxidants

Topical Vitamin C Protects Skin from Ultraviolet Radiation-Induced Damage

Photoaging — Update and Treatment, Sheldon R. Pinnell

Skin Care References for Skinceuticals Serum 20 AOX+


	*72,000+ expert documents for the skincare aficionado.* Home View Cart/Checkout Contact/Customer Service Perennial / Wisdoms UV Exposure Aging Skin and Mature Skin Theories of Aging Antioxidants Sunscreens Skin Care Allergan Alyria Anthelios Avene Biomedic Blue Lizard Bull Frog Cellex-C Citrix Clarisonic Colorescience Cotz Clinique Medical DCL Dermatix Elastiderm Elta MD Estion Ethocyn Exuviance Fake Bake Frederic Fekkai Glycolix Glytone Great Lips Rx Heliocare IS Clinical Jane Iredale Jan Marini Kinerase Kinerase Clear Kinerase PhotoFacials Kinerase Pro+ Leaf & Rusher La Roche Posay L-M-X M Lab Neoceuticals Neocutis Neostrata Neova Nia24 Nordic Naturals Obagi Obagi Clenziderm Obagi Professional-C Obagi Rosaclear OC Eight Olos PCA Skin Pentaxyl Prevage MD Remergent Replenix RevaleSkin Revitalash Scarguard Skinceuticals SkinMedica Teamine Theraplex Ti-Silc / Z-Silc Topix Tricomin VitaMedica Zeno MD Browse more brands. Facial Skin Condition Treatments Adult Acne Broken Capillaries Dark Circles Deep Wrinkles Dry Skin Fine Lines Hyperpigmentation Open Pores Puffy Eyes Rosacea Sagging Skin Body Skin Condition Treatments Aging Hands Breast Firming Cellulite Hands Keratosis Pilaris Lips Scalp Acne Stretch Marks Skin Care Ingredients Alpha Lipoic Acid Arginine + Serine Asiatic Acid Blueberry Caffeine Capryloyl Salicylic Acid Ceramides Chlorogenic Acid Chrysin Coffee Berry Hydrolyzed Hyaluronic Acid Mexoryl Pro-Xylane Silymarin Sodium Laureth Sulfate/Sulphate Browse more ingredients. Clinical Procedures and Topics Four Fundamentals Absurd Skin Care Aging Skin Antioxidants Botox Enzyme Exfoliation Free Radical Damage French Skin Care Glycolic Acid Idebenone Irrational Fears Klein Becker Oxidative Stress Paula Begoun Perricone Restylane Skin Structure Stem Cells Healthy Skin Barrier Function Smoking Sun Protection Topical Vitamin C/Firming Choices and Needs Strivectin Additional clinical skincare topics. absorption acid acne addition additional against aging anti antioxidant antioxidants apply ascorbic ascorbyl available bioclear body care class clinical code collagen combination compared concentration containing cream daily damage deeper defense delivery effective effects enhanced esta evening face facial ferulic fine firming free greater healthy http images information ingredients levels lhnv light lines lotion magazine marini normal noshade obagi oily once open order palmitate particularly patients penetrating penetration phloretin photoaging photoprotection pores prevent primary product production products professional protection provide results retinol sensitive serum serums size skin skincare skinceuticals stable states sunscreen sunscreens topical treatment united used using vitamin vspace within
			Skinceuticals Serum 20 AOX+ Suitability and performance are not guaranteed outside of an ongoing individualised protocol. Instructions for Use of Serum 20 AOX+ by Skinceuticals Enhancing Absorption and Penetration of Topical Vitamin C Ingredients for Skinceuticals Serum 20 AOX+ Skinceuticals Serum 20 AOX+ Supply Notes Skinceuticals Antioxidant Storage Notes — Protective/Preservative Refrigeration Skinceuticals Serum 20 — Media Antioxidant Outline Refined to Focus on Primary Antioxidants Topical Vitamin C Protects Skin from Ultraviolet Radiation-Induced Damage Photoaging — Update and Treatment, Sheldon R. Pinnell Skin Care References for Skinceuticals Serum 20 AOX+ Formulated at the precise concentration proven to deliver maximum amounts of antioxidant vitamin C to the skin, Skinceuticals Serum 20 contains 20% pure stabilized L-ascorbic acid to: increase collagen and elastin production for firmer skin and tightened pores; prevent premature signs of aging; tighten visibly open pores; help protect against damaging UVA/UVB rays when used with a true broad spectrum sunscreen. This antioxidant treatment is lightweight, fast-absorbing, and suitable for all skin types and conditions excluding wide-spread active acne (these patients are recommended C + AHA or Jan Marini C-ESTA Oil Control Serum instead). May function as a strong exfoliant. Ideal for normal to oily and normal to dry skin. Patients with significantly dry-prone skin will prefer C E Ferulic, which provides additional antioxidant benefits. Skinceuticals Serum 20 Benefits: Proven to deliver the highest levels of vitamin C to the skin — for reasons unknown, concentrations above 20% actually reduce absorption: Antioxidant and nutritive effects reduce the appearance of fine lines and wrinkles, neutralise free radicals to prevent oxidation, provide photoprotection in addition to that brought by sunscreens, and stimulate collagen synthesis; Once absorbed, can’t be washed or rubbed off, remaining protective for up to four days; Dramatically improves skin tone and elasticity. Obagi Professional-C Serums are claimed to be more stable and deeper-penetrating for enhanced antioxidant protection, particularly against UVA, when compared with the deepest penetrating Skinceuticals Serum, Skinceuticals Serum 20 AOX+. Individual results vary. Please note: Skinceuticals is available for online order by customers in the United States only. This product ships from the United States. Australian patients can re-order select Skinceuticals products for delivery within Australia in accordance with their prescription by logging in. $214.70 \| 1 fl. oz. / 30 mL Login to reorder. Not available all regions or without consultation. Forestall unnecessary skin deterioration by using this product in a manner which does not constitute skin care failure. Wednesday, 14 November 2007 Instructions for Use of Serum 20 AOX+ by Skinceuticals Keep Skinceuticals Serum 20 AOX+ refrigerated. Apply 4-5 drops of Skinceuticals Serum 20 AOX+ to the face and neck once daily to dry skin after having used an appropriate cleanser. Always follow application of Skinceuticals Serum 20 AOX+ with Skinceuticals B5 Gel. (and a Phyto Serum in case of hyperpigmentation). In the morning finish with a corrective or basic maintenance moisturizer and/or true broad spectrum sunscreen. In the evening, finish with corrective or basic maintenance moisturizer alone. May also be used with Skinceuticals Renew Overnight Resurfacing Treatments in the evening. Sunday, 23 March 2008 Enhancing Absorption and Penetration of Topical Vitamin C Enhancing the absorption and penetration of skin care products containing topical Vitamin C, such as Jan Marini C-ESTA, Skinceuticals C E Ferulic and a range of other formulations from IS Clinical, is easy and leads to improvements in: firmness; skin texture; skin tone; colouring. To achieve improved absorption: Always ensure skin is free of stifling dead skin cells by making regular use of an evenly acting and thorough exfoliating product containing either one or more of glycolic, salicylic acid or proteolytic enzymes. If using topical Vitamin C during the day, try applying the Vitamin C, waiting 30 seconds to one minute, then applying an appropriate exfoliating product on top (see below) before finishing with a moisturizer/sunscreen (see below). These recommendations are especially helpful in improving wear in those individuals with very oily, very dry or sensitive skin. Recommended protocols for improved absorption of topical Vitamin C (AM and/or PM) *Normal to Dry or Combination Skin using Jan Marini* C-ESTA Serum + Bioclear Lotion + Age Intervention Cream/Serum and/or Antioxidant Daily Face Protectant SPF 30. *Uniformly Very Dry Skin using Jan Marini* Jan Marini C-ESTA Cream + Bioclear Cream + Age Intervention Cream/TGF Cream and/or Antioxidant Daily Face Protectant SPF 30. *Uniformly Very Oily Skin using Jan Marini* C-ESTA Serum or Oil Control Serum + Bioclear Lotion + TGF Serum and/or Jan Marini Antioxidant Daily Face Protectant SPF 30. *Normal to Dry or Combination Skin using Skinceuticals* Skinceuticals C E Ferulic + Skinceuticals Intense Line Defense + Skinceuticals Sunscreen SPF 20 or 30. *Uniformly Very Dry Skin using Skinceuticals* Skinceuticals C E Ferulic + Skinceuticals Intense Line Defense + Skinceuticals Skin Firming Cream (younger very dry skin) or Face Cream (peri/post-menopausal very dry skin) + Skinceuticals Sunscreen SPF 20 or 30. *Uniformly Very Oily Skin using Skinceuticals* Skinceuticals Serum 10, 15 or 20 AOX + Skinceuticals Intense Line Defense + Skinceuticals Daily Sun Defense SPF 20. Notes: In the evening the same advice and protocols apply in all cases, just omitting sunscreen. Skinceuticals Topical Vitamin C is used once daily maximum; Jan Marini C-ESTA may be used twice daily. Skinceuticals Renew Overnight Cream for Normal to Dry or Normal to Oily Skin may be used in addition to Skinceuticals Intense Line Defense in the evening for more diverse benefits. Additional Related References: Skinceuticals Vitamin C Serums — General Advice; Jan Marini Bioglycolic Facial Lotion without a Jan Marini Hydrator; Applying Jan Marini C-ESTA Facial Skin Care Products; Ways of Using Jan Marini C-ESTA Oil Control Serum; Improving Tone and Wear of Sunscreens; Skinceuticals Antioxidant Serums — Primary Benefits to Skin Health; Skinceuticals Serum 20 Media; Waiting Between Layers — A Path to Better Results. Thursday, 9 November 2006 Ingredients for Skinceuticals Serum 20 AOX+ Water, L-Ascorbic acid, ethoxydiglycol, propylene glycol, glycerin, zinc sulfate, phenoxyethanol, ferulic acid, panthenol, sodium hyaluronate, sodium hydroxide. Wednesday, 28 November 2007 Skinceuticals Serum 20 AOX+ Supply Notes In warmer weather, Skinceuticals Serum 20 AOX+ is despatched contained within heat insulated (polyester foil) packaging. Monday, 13 July 2009 Skinceuticals Antioxidant Storage Notes — Protective/Preservative Refrigeration In warmer weather, and perhaps all year round, it's best to store Skinceuticals Antioxidant Serums under darkened refrigeration to preserve and extend their ingredients' potential. Additional environmentally-related supply notes: Skinceuticals Eye Gel AOX+; Skinceuticals Serum 10 AOX+; Skinceuticals Serum 15 AOX+; Skinceuticals Serum 20 AOX+; Skinceuticals C + AHA; Skinceuticals C E Ferulic. Wednesday, 24 May 2006 Skinceuticals Serum 20 — Media InStyle Magazine, June 2005 In the June issue of InStyle Magazine, singer Sheryl Crow claims Skinceuticals Sport UV Defense SPF 45 is a summer survival necessity [used with Skinceuticals Serum 20]. The Early Show, June 2004 Vitamin C is important for healthy skin. Studies show that in addition to increasing collagen growth it also helps to neutralize the factors that damage your skin on a daily basis. SkinCeuticals Vitamin C Serums are recommended as an effective topical treatment. Delta Sky Magazine, August 2003 Delta explains how difficult it is to stabilize Vitamin C; with this in mind they recommend SkinCeuticals Vitamin C formulations as an effective version. We know that Vitamin C has to be in a pure and stable formulation to be effective, lucky for us that SkinCeuticals has such a product. Allure Magazine, January 2002 Need some Rosacea relief? Allure recommends using a SkinCeuticals Vitamin C Serum to help heal broken capillaries and keep a nice even skin tone. Sunday, 20 January 2008 Antioxidant Outline Refined to Focus on Primary Antioxidants Due to the increasing number of skin care products which provide antioxidant function, and because "antioxidant" increasingly refers to any substance which potentially prevents any degree of damage from reactive oxygen species, the listing of antioxidant skin care products now distinguishes between primary antioxidants for various skin types and conditions, and all antioxidants by brand. Skin care featuring primary antioxidants are those which provide the key phytochemicals (carotenoids, tocopherols, vitamin c among others) which are key among the body's native defense systems and have a very clear antioxidant function and high potency. Products containing beneficial antioxidants which are not as important as those designated as being primary are listed as part of the complete summary. The change reflects our background in molecular and cellular biology — primary antioxidants have clearly established and irreplaceable benefits. See Idebenone — Prevage and Priori vs C E Ferulic for a perfect illustration of this reality. Related Nodes: Anthocyanins in Blueberries and Strawberries; An Introduction to Skinceuticals Topical Antioxidant Therapy; Skinceuticals Antioxidant Protection - Serums Comparison Graph. Tuesday, 15 December 2009 Topical Vitamin C Protects Skin from Ultraviolet Radiation-Induced Damage Ultraviolet radiation damage to the skin is due, in part, to the generation of reactive oxygen species (free radicals). Vitamin C (l-ascorbic acid) functions as a biological co-factor and antioxidant due to its reducing properties. Topical application of vitamin C has been shown to elevate significantly cutaneous levels of this vitamin in skin, and this correlates with protection of the skin from UV damage as measured by erythema and sunburn cell formation. This protection is biological and due to the reducing properties of the molecule. Further, vitamin C levels of the skin can be severely depleted after UV irradiation, which lower the skin's innate protective mechanism as well as leaving it at risk of impaired healing after photoinduced damage. In addition, vitamin C protects skin from UVA-mediated phototoxic reactions (PUVA) and therefore shows promise as a broad-spectrum photoprotectant. Effective ascorbic acid photoprotective agents include Skinceuticals C E Ferulic, other Skinceuticals Antioxidants such as Serum 15 AOX+ from the revised AOX+ collection and related products from IS Clinical. Ectoin is also effective against the skin registering sun damage and may be used in association with ascorbic acid serums. Reference: Farris Patricia K., MD. (2005) Topical Vitamin C: A Useful Agent for Treating Photoaging and Other Dermatologic Conditions. Dermatologic Surgery 31:s1, 814-818. Ascorbic acid is also of assistance in treating broken capillaries. Contact a Melbourne Dermatology expert through live help for assistance or printed materials. Skinceuticals C E Ferulic — Maximal Primary Antioxidants 30 mL/1 Fl. Oz. Skinceuticals Eye Gel AOX+ — Firming Eye Contour Primary Antioxidant Skinceuticals Serum 15 AOX+ — Firming Primary Antioxidant Tuesday, 7 July 2009 Photoaging — Update and Treatment, Sheldon R. Pinnell antioxidants, photoprotection, photoaging, ultraviolet light, aging skin."> Sheldon R. Pinnell, M.D., J. Lamar Callaway Professor, Dermatology. New methods of photoprotection are needed to curb the epidemic of skin cancer — an epidemic worsened by an aging population, ever-increasing outdoor activities and escalating immunosuppression related to medical treatments. Sunscreens are not the complete answer. Recent studies point out that in actual usage individuals apply only 20-25% the amount used to determine SPF values. Since SPF is an exponential function, actual protection is no more than three to fourfold at this level of application for any sunscreen. Moreover, the best sunscreens available only protect against 55% of free radicals generated in skin by ultraviolet irradiation. The skin naturally protects itself from the sun with antioxidants. These include vitamin C in fluids and vitamin E in stratum corneum and membranes. My research laboratory is interested in developing antioxidant formulations that can be applied to skin to increase the natural reservoir and provide additional photoprotection. Since antioxidants are naturally unstable compounds, they provide challenges for formulation. To work, they must be chemically stable, they must get into skin, and they must be used at meaningful concentrations. Finally, they must be effective at providing photoprotection. L-ascorbic acid (vitamin C) can be used topically, but proper formulation is crucial. It must be at a pH below 3.5 in order to enter skin. It is maximally effective for increasing skin levels at a concentration of 20%. Skin can be saturated in 3 days, and following saturation, half life of removal is about 4 days. It is effective for protecting the skin against UVB and UVA and can protect against UV-immunosuppression. Alpha tocopherol (vitamin E) can enter skin when applied topically. Maximal percutaneous absorption occurs at 1% concentration. Alpha tocopherol is effective for protecting skin against photoinjury, photocarcinogenesis and UV-immunosuppression. Because vitamin C and vitamin E are relatively unstable in topical formulations, derivatives (esters) have been synthesized to improve stability. Vitamin C derivatives include ascorbyl palmitate and magnesium ascorbyl phosphate. Vitamin E derivatives include tocopherol acetate. These derivatives must then be converted in tissue, back to the vitamin to be effective. These derivatives are successfully converted in the stomach when used in vitamin pills, but not readily converted when used topically for skin protection. In the human body, antioxidants function as an interactive network, with chemical reconstitution of antioxidants after they are oxidized during protective functions. As a network they work synergistically. Vitamin C and vitamin E, when formulated together at maximal concentrations for percutaneous absorption, provide synergistic photoprotection for skin when applied topically. We have recently discovered that ferulic acid provides added chemical stability to a solution of vitamin C and vitamin E. When heated at 45¼C for one month, vitamin E is 100% stable and vitamin C is more than 90% stable. Ferulic acid is a ubiquitous plant antioxidant and is also used in making plant cell walls. A solution of 15% L-ascorbic acid, 1% alpha tocopherol and 0.5% ferulic acid provides eight- to ten-fold protection against solar-simulated irradiation of skin. Protection is demonstrated for erythema, sunburn cell formation, caspase-3 and caspase-7 activation and thymine dimer formation. Thymine dimers are critical DNA mutations intimately involved in skin cancer formation. In summary, topical vitamins C and E stabilized with ferulic acid provide synergistic photoprotection for skin and prevent thymine dimer formation. Derivatives of vitamins C and E are not readily converted to free vitamins when used topically. Photoaging — Update and Treatment, Sheldon R. Pinnell Reference List Pinnell SR: Cutaneous photodamage, oxidative stress, and topical antioxidant protection. Journal of the American Academy of Dermatology. 2003, 48: 1-19. Lin, J-Y et al.: UV photoprotection by combination topical antioxidants vitamin C and vitamin E . Journal of the American Academy of Dermatology. 48 :866-74, 2003. Lin J.Y., Lin, F-Y, Burch, J.A., Gupta, R., Grichnik, J.M., Monteiro-Riviere, N.A., Zielinski, J., and Pinnell, S.R. Ferulic Acid Stabilizes a Topical Solution Containing Vitamins C+E and Doubles its Photoprotection for Skin , J Invest Dermatol 122 :883, 2004. Lin, F-Y, Monteiro-Riviere, N.A., Grichnik, J.M., Zielinski, J.E., and Pinnell, S.R. A Topical Antioxidant Solution Containing Vitamin C, Vitamin E, and Ferulic Acid Prevents Ultraviolet Radiation-Induced Caspase-3 Induction in Skin , J Invest Dermatol 122 :883, 2004. Tuesday, 7 November 2006 Skin Care References for Skinceuticals Serum 20 AOX+ Obagi Professional-C Serum 5% Obagi Professional-C Serum 10% Obagi Professional-C Serum 15% Obagi Professional-C Serum 20% Sagging Skin Sagging Skin Treatments — Arranged by Potency Sagging Skin Protocol for Oily Skin Skinceuticals Serum 20 — Maximum Firming Antioxidant Skinceuticals Phloretin CF Skinceuticals Phloretin CF Vitamin C Content — Skin Firming and Acne Skinceuticals C E Ferulic — Maximal Primary Antioxidants 30 mL/1 Fl. Oz. Skinceuticals Serum 20 — Media Skinceuticals Eye Gel AOX+ — Firming Eye Contour Primary Antioxidant Skinceuticals Serum 15 AOX+ — Firming Primary Antioxidant Skinceuticals Serum 10 AOX+ — Extra Gentle Firming Primary Antioxidant Skinceuticals C + AHA — Resurfacing Firming Primary Antioxidant Skinceuticals Active UV Defense SPF 15 Instructions for Use Skinceuticals Hydrating B5 Gel Skinceuticals C E Ferulic — Dermatological Evaluation of Tolerance and Efficacy Skinceuticals C E Ferulic — Evaluation of Effects on Special Molecular Biomarkers of Oxidative Stress in Skin of Healthy Subjects After UVA 1 Irradiation Open Pores Enhancing Absorption and Penetration of Topical Vitamin C Obagi Medical Products Presents In Vitro Data Showing Its Topical Vitamin C Serums Provide Greater Absorption and Stability Than a Leading Competitor Different Sunscreens provide Different Skin Protection Open Pores — Quick Fix Treatment and Lasting Prevention Propensity for Vitamin C (as Ascorbic Acid) to Stimulate Acne Topical L-Ascorbic Acid: Percutaneous Absorption Studies (Dermatol Surg. 2001;27:137-142) Photoprotected Smoker's Skin Ascorbic Acid vs. Ascorbyl Palmitate (2008) Obagi vs. Skinceuticals Best Treatment for Stubborn Hyperpigmentation Skinceuticals Serum 20 Related Skin Care Information, Products and Expert Discussions Skinceuticals Serum 15 AOX+ — Firming Primary Antioxidant Skinceuticals Serum 10 AOX+ — Extra Gentle Firming Primary Antioxidant Skinceuticals Eye Gel AOX+ — Firming Eye Contour Primary Antioxidant Skinceuticals C + AHA — Resurfacing Firming Primary Antioxidant Skinceuticals Skin System 3 — Clarify Skinceuticals : Skinceuticals Serums - Topical Antioxidants : An Introduction to Skinceuticals Topical Antioxidant Therapy : Skinceuticals Antioxidant Serums — Primary Benefits to Skin Health and Condition : Understanding Photoprotection : Skinceuticals Phloretin CF : Skinceuticals C E Ferulic — Maximal Primary Antioxidants 30 mL/1 Fl. Oz. : Skinceuticals Serum 20 AOX+ : Skinceuticals Serum 15 AOX+ — Firming Primary Antioxidant : Skinceuticals Serum 10 AOX+ — Extra Gentle Firming Primary Antioxidant : Skinceuticals C + AHA — Resurfacing Firming Primary Antioxidant : Skinceuticals Eye Gel AOX+ — Firming Eye Contour Primary Antioxidant : Skinceuticals Vitamin C Serums — General Advice : Skin Care References for Skinceuticals Serums - Topical Antioxidants : Discontinued Skinceuticals Serums (Pre-Ferulic Acid/AOX+) : File Skinceuticals Serum 20 AOX+ for reference.