Skin Care and Treatments of Melbourne Dermatology - Loss of Elastic Fibers Causes Skin Wrinkles (in Sun-Damaged Human Skin)

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Loss of Elastic Fibers Causes Skin Wrinkles (in Sun-Damaged Human Skin)

Loss of Elastic Fibers Causes Skin Wrinkles (in Sun-Damaged Human Skin) — Healthy  Loss of Elastic Fibers Causes Skin Wrinkles (in Sun-Damaged Human Skin) — Typical

Image: Mature Skin Analysis. For a video illustration, see La Roche Posay — Aging Skin Video: Deep Wrinkles, Loss of Firmness.


Results from the Journal of Dermatological Science indicate that a loss of skin's elastin is a fundamental cause of wrinkles and that retinol physically reverses this aging change by restoring the same lost and damaged elastin required for the absence of wrinkles.

Skin's elastin is primarily destroyed by visible and invisible daylight, and possibly by computer screen radiation, in a process known as photoaging.

Accordingly, you can progressively reverse existing wrinkled damage and prevent future wrinkling changes to skin by implementing ideal photoprotection and retinol together.

It is important to remember that retinoids are not a sole answer to aging skin's needs and that they may cause dermatitis, disrupt healthy barrier function to lessen epidermal attractiveness and are photosensitizing in the absence of ideal skin care factors.

Do not implement retinol on its own, particularly in the absence of ideal sunscreen use.

Retinoids are compared in Retinoid vs. Retinoid — Jan Marini, Skinceuticals, Gernetic 6 Month Programs and Visia Analysis.

Skinceuticals Retinol appears to provide some potential benefits over prescription retinoids, which are frequently poorly tolerated and fail to provide ideal benefit if use is inconsistent.

Benefits of Skinceuticals Retinol over prescription retinol generally pertain to the Supplementary Anti-Inflammatory Properties of Skinceuticals Retinol and the gentler manner in which it becomes useful within skin.

Review the order of application for retinoids.

Generally avoid layering alpha hydroxy acids and retinoids.

For ideal photoprotection, refer to the following sunscreen topics:

Reapplication of sunscreen during the day is often desirable — a sunscreen brush is the easiest way to do this.

Retinol is also of benefit to aging hands.

Do not implement retinoids without first seeking advice as contraindications exist and avoid use in a manner constituting skin care failure.

Loss of Elastic Fibers Causes Skin Wrinkles in Sun-Damaged Human Skin

Although wrinkling is the most obvious sign of aged skin, the detailed pathomechanism of wrinkle development has not been elucidated.

In this study, we investigated the role of elastic fibers in the formation of skin wrinkles.

Loss of elastic fibers was measured quantitatively in the facial skins of subjects representing seven decades, and then compared with wrinkle severities.

We also investigated whether topical retinoic acid treatment to photoaged human skin can restore destroyed elastic fiber, and the correlation between wrinkle improvement with increase in elastic fibers in RA-treated facial skin.

We found a significant correlation between decreases in the length, width, number and total area of oxytalan fibers and wrinkle severity.

Furthermore, we found that topical application of retinoic acid (0.025%) to chronically photodamaged skin regenerated and restored elastic fibers, and that there was a significant positive correlation between the amount of newly regenerated elastic fiber and the wrinkle improvement caused by retinoic acid.

Our results provide an objective insight into the role of elastic fibers in skin wrinkle formation by providing a quantitative correlation between changes in oxytalan fibers and the severity of skin wrinkling.


Loss of elastic fibers causes skin wrinkles in sun-damaged human skin.

Jin Young Lee, Yeon Kyung Kim, Jin Young Seo, Chong Won Choi, Jae Sung Hwang, Byeong Gon Lee, Ih Seop Chang, Jin Ho Chung.

Journal of dermatological science 1 May 2008 (volume 50 issue 2 Pages 99-107 DOI: 10.1016/j.jdermsci.2007.11.010).

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Decrease Wrinkles : SkinMedica TNS : Loss of Elastic Fibers Causes Skin Wrinkles (in Sun-Damaged Human Skin) : Deep Wrinkles : Fine Lines : Palmitoyl Oligopeptide : Effect of Skinceuticals Intense Line Defense's Lactic Acid Content on Skin Hydration/Volume/Fine Lines/Deeper Wrinkles : Wrinkle Prevention :


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